878547-68-3

Upstream product

• 75-15-0 carbon disulfide 
• 93-68-5 3-oxo-N-o-tolylbutanamide 
• 109-64-8 1,3-dibromo-propane 
• 682360-46-9 2-(1,3-dithian-2-ylidene)-3-oxobutanoic acid 
• 19607-51-3 ethyl 2-(1,3-dithian-2-ylidene)-3-oxobutyric acid 
• 748150-28-9 2-(1,3-dithian-2-ylidene)-3-oxobutyric acid chloride 
• 95-53-4 o-toluidine 

Relevant academic research and scientific papers

Catalytic synthesis of α-Oxoketene S,S-acetals in a wet ionic liquid [Bmim]Cl/H2O homogeneous system

A clean, practical and environmentally friendly synthesis in a homogeneous system has been developed for α-oxoketene S,S-acetals. A mixture of [Bmim]Cl and water was used as medium. The best economical and practical molar ratio of [Bmim]Cl to substrate was 4 to 1. With various types of 1,3-dicarbonyl compounds as substrate, the corresponding α-oxoketene S,S-acetals have been prepared under mild reaction conditions with yields of 53-74% after purification with silica gel column. [Bmim]Cl/water can be recycled several times.

A facile synthetic route to highly functionalized 2,4-pyrrolidinediones: A new base-catalyzed cyclization

2,4-Pyrrolidinedione derivatives were synthesized in 67-85% yield in one-pot reaction via base-catalyzed cyclization of α-(arylvinylcarbonyl)-α′-(N-arylaminocarbonyl)ketene dithioacetals formed in situ by the reaction of a-acetyl-α′-(N-arylaminocarbonyl)k

A clean, facile and practical synthesis of α-oxoketene S,S-acetals in water

A clean, facile and practical synthesis of α-oxoketene S,S-acetals in water has been developed. Catalyzed by tetrabutylammonium bromide (TBAB) at room temperature in water, a range of β-dicarbonyl compounds have been converted to the corresponding α-oxoke