878809-98-4

Upstream product

• 3934-20-1 2,6-Dichloropyrimidine 
• 3764-01-0 2,4,6-trichloropyrimidine 
• 144432-85-9 3-chloro-4-fluorophenylboronic acid 

Downstream Products

• 833463-04-0 2-chloro-4-(3-chloro-4-fluoro-phenyl)-6-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-pyrimidine 
• 1117949-04-8 2-chloro-4-(3-chloro-4-fluorophenyl)-6-(4-(1-methyl-1H-imidazol-2-yl)-piperazin-1-yl)-pyrimidine 
• 878809-97-3 4-[2-chloro-6-(3-chloro-4-fluoro-phenyl)-pyrimidin-4-yl]-piperazine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

BIARYL PIPERAZINYL-PYRIDINE ANALOGUES

Biaryl piperazinyl -pyri dine analogues are provided, of the Formula (I): wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands, for receptor localization studies.