87906-18-1

Upstream product

• 87542-16-3 (2RS,3RS)-1-(2,4-dimethoxybenzyl)-3-(2-methyl-1,3-dioxolan-2-yl)-4-oxoazetidine-2-carboxylic acid 
• 105995-50-4 magnesium 4-nitrobenzyl malonate 
• 87542-18-5 [(2S,3R)-1-(2,4-Dimethoxy-benzyl)-3-(2-methyl-[1,3]dioxolan-2-yl)-4-oxo-azetidin-2-yl]-acetic acid 

Downstream Products

• 87542-45-8 p-nitrobenzyl (5RS,6SR)-2-(2-formylaminoethylthio)-6-(2-methyl-1,3-dioxolan-2-yl)carbapen-2-em-3-carboxylate 
• 87542-46-9 p-nitrobenzyl (3RS,5RS,6SR)-6-(2-methyl-1,3-dioxolan-2-yl)-2-oxocarbapenam-3-carboxylate 

Relevant academic research and scientific papers

Simple and Condensed β-Lactams. Part 5. The Synthesis of some (5RS,6SR)-2-(Formylaminoethylthio)-6-(2-methyl-1,3-dioxolan-2-yl)carbapenem-3-carboxylic Acid Derivatives and Related Compounds

Starting with the 4-oxoazetidine-2-carboxylic acids (3a) and (3b), methods for the synthesis of derivatives of the racemic carbapenem-3-carboxylic acid (2), an analogue of the potent antibiotic thienamycin have been developed.The synthetic steps included