879222-13-6

Basic information

• Product Name: Carbamic acid, [2-[(3-chlorophenyl)methoxy]-6-methyl-4-pyridinyl]-, 1,1-dimethylethyl ester
• CAS NO: 879222-13-6
• Molecular Formula: C18H21ClN2O3
• Molecular Weight: 348.829
• Mol File: 879222-13-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [2-[(3-chlorophenyl)methoxy]-6-methyl-4-pyridinyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [2-[(3-chlorophenyl)methoxy]-6-methyl-4-pyridinyl]-, 1,1-dimethylethyl ester(879222-13-6)
• EPA Substance Registry System: Carbamic acid, [2-[(3-chlorophenyl)methoxy]-6-methyl-4-pyridinyl]-, 1,1-dimethylethyl ester(879222-13-6)

Safety Data

• Hazardous Substances Data: 879222-13-6(Hazardous Substances Data)

Upstream product

• 873-63-2 m-chlorobenzyl alcohol 
• 25462-85-5 2-chloro-6-methylpyridine-4-carboxylic acid 
• 879222-11-4 2-(3-chlorobenzyloxy)-6-methylisonicotinic acid 
• 75-65-0 tert-butyl alcohol 

Relevant articles and documents

Arylmethoxypyridines as novel, potent and orally active mGlu5 receptor antagonists

Optimisation of affinity, chemical stability, metabolic stability and solubility led from a chemically labile HTS hit 1 to mGlu5 receptor antagonists (24-26) with high affinity for the allosteric MPEP binding site, improved microsomal metabolic stability and anxiolytic-like activity in vivo as assessed by the Vogel conflict drinking test.