87929-13-3Relevant academic research and scientific papers
Synthesis and Anti-inflammatory Activity of a Few 5-(Indan-1'yl)methyltetrazoles
Roy, A.,Gupta, J. K.,Lahiri, S.C.
, p. 377 - 380 (2007/10/02)
In an attempt to develop relatively less toxic and more potent anti-inflammatory agents than the presently available ones, a few 5-(indan-1'-yl)methyltetrazoles have been synthesised and subjected to anti-inflammatory screening.Two of them showed anti-inflammatory potency close to that of phenylbutazone in both acute (carrageenin-induced edema) and chronic (adjuvant-induced arthritis) animal test models.The compounds have high LD50 and high therapeutic index, and appreciable analgesic and antipyretic activity
