879339-90-9

Upstream product

• 23074-36-4 2-bromobutene 
• 762287-59-2 (3-fluoro-2-methoxyphenyl)boronic acid 

Downstream Products

• 950519-61-6 ethyl (E,R)-4-(3-fluoro-2-methoxyphenyl)-2-hydroxy-2-(trifluoromethyl)-hex-4-enoate 
• 949900-78-1 ethyl (E/Z),(R)-4-(3-fluoro-2-methoxyphenyl)-2-hydroxy-2-(trifluoromethyl)-hex-4-enoate 

Relevant academic research and scientific papers

Discovery of new selective glucocorticoid receptor agonist leads

We report on the discovery of two new lead series for the development of glucocorticoid receptor agonists. Firstly, the discovery of tetrahydronaphthalenes led to metabolically stable and dissociated compounds. Their binding mode to the glucocorticoid rec

Cyclic phenyl-substituted indazols, a process for their production and their use as anti-inflammatory agents

The present invention relates to the compounds of formula I, processes for their production and their use as anti-inflammatory agents.

Tetrahydronaphthalene derivates, processes for preparing them and their use as antiinflammatory agents

The invention relates to multiply substituted tetrahydronaphthalene derivatives of the formula (Ia) to processes for preparing them and to their use as antiinflammatory agents.