879473-33-3

Upstream product

• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 321706-24-5 N-[2-(3,4-dimethoxyphenyl)ethyl]-4-nitrobenzenesulfonamide 
• 50-00-0 formaldehyd 

Downstream Products

• 1615201-31-4 (1-(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)sulfonyl)phenyl)-1H-1,2,3-triazol-4-yl)methanol 
• 1615201-32-5 6,7-dimethoxy-2-((4-(4-(phenoxymethyl)-1H-1,2,3-triazol-1-yl)phenyl)sulfonyl)-1,2,3,4-tetrahydroisoquinoline 
• 1615201-34-7 6,7-dimethoxy-2-((4-(4-((o-tolyloxy)methyl)-1H-1,2,3-triazol-1-yl)phenyl)sulfonyl)-1,2,3,4-tetrahydroisoquinoline 
• 1615201-35-8 6,7-dimethoxy-2-((4-(4-((p-tolyloxy)methyl)-1H-1,2,3-triazol-1-yl)phenyl)sulfonyl)-1,2,3,4-tetrahydroisoquinoline 
• 1615201-36-9 1-(2-((1-(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)sulfonyl)phenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)ethanone 
• 1615201-37-0 methyl 2-((1-(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)sulfonyl)phenyl)-1H-1,2,3-triazol-4-yl)methoxy)benzoate 
• 1615201-38-1 4-((1-(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)sulfonyl)phenyl)-1H-1,2,3-triazol-4-yl)methoxy)benzaldehyde 
• 1615201-39-2 6,7-dimethoxy-2-((4-(4-((4-nitrophenoxy)methyl)-1H-1,2,3-triazol-1-yl)phenyl)sulfonyl)-1,2,3,4-tetrahydroisoquinoline 
• 1615201-40-5 3-((1-(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)sulfonyl)phenyl)-1H-1,2,3-triazol-4-yl)methoxy)-4-methoxybenzaldehyde 
• 1615201-41-6 4-((1-(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)sulfonyl)phenyl)-1H-1,2,3-triazol-4-yl)methoxy)-3-methoxybenzaldehyde 
• 1615201-42-7 2-((4-aminophenyl)sulfonyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 1615201-44-9 2-((4-azidophenyl)sulfonyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 

Relevant academic research and scientific papers

Synthesis and molecular docking of 1,2,3-triazole-based sulfonamides as aromatase inhibitors

Abstract A series of 1,4-disubstituted-1,2,3-triazoles (13-35) containing sulfonamide moiety were synthesized and evaluated for their aromatase inhibitory effects. Most triazoles with open-chain sulfonamide showed significant aromatase inhibitory activity

Novel 1,4-naphthoquinone-based sulfonamides: Synthesis, QSAR, anticancer and antimalarial studies

A novel series of 1,4-naphthoquinones (33-44) tethered by open and closed chain sulfonamide moieties were designed, synthesized and evaluated for their cytotoxic and antimalarial activities. All quinone-sulfonamide derivatives displayed a broad spectrum o

Design, synthesis and molecular docking studies of novel N-benzenesulfonyl-1,2,3,4-tetrahydroisoquinoline-based triazoles with potential anticancer activity

A novel series of N-benzenesulfonyl-1,2,3,4-tetrahydroisoquinolines (14-33) containing triazole moiety were designed and synthesized through rational cycloadditions using the modified Pictet-Spengler reaction and the Click chemistry. Antiproliferative act

Tungstophosphoric acid catalyzed synthesis of N-sulfonyl-1,2,3,4- tetrahydroisoquinoline analogs

An operationally simple and eco-friendly protocol has been developed for the synthesis of N-sulfonyl-1,2,3,4-tetrahydroisoquinolines 3 using the modified Pictet-Spengler reaction of N-sulfonylphenylethylamines 1 and various aldehydes 2 in the presence of