879560-07-3

Usage

Also known as

Kadsurenone

Class of organic compounds

Phenylbutadiynes

Derivative of

4-methoxybenzyl alcohol and 4-phenylbutadiyne

Found in

Plant species such as Kadsura coccinea and Nandina domestica

Properties

Potential anti-inflammatory and antioxidant properties

Investigated for

Potential use in the treatment of neurological disorders and cancer due to its ability to modulate certain biological pathways

Upstream product

• 19115-30-1 1-(4-methoxyphenyl)-2-propyn-1-ol 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 879560-02-8 (1,1-dibromobut-1-en-3-yn-2-yl)benzene 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 1257555-45-5 (E)-1-(4-methoxyphenyl)-5-phenylpent-2-en-4-yn-1-one 
• 56558-79-3 1-(4-Methoxy-phenyl)-5-phenyl-penta-2,4-diyn-1-one 

Relevant academic research and scientific papers

Stereoselective synthesis of enynones via base-catalyzed isomerization of 1,5-disubstituted-2,4-pentadiynyl silyl ethers or their alcohol derivatives

1,5-Disubstituted-2,4-pentadiynyl silyl ethers undergo smooth desilylative isomerization to afford cis-enynones as major products with moderate stereoselectivities in the presence of a catalytic amount of KOtBu or DBU. While the isomerization reactions of their alcohol derivatives catalyzed by KOH, KOtBu or NaH take place efficiently to produce trans-enynones with high stereoselectivities. These reactions provide convenient and practical routes for the synthesis of enynones with a wide range of substitution groups.

One-pot formation and derivatization of di- and triynes based on the Fritsch-Buttenberg-Wiechell rearrangement

(Chemical Equation Presented) A divergent, one-pot synthesis of functionalized polyynes has been developed. Beginning with the appropriately substituted dibromoolefinic precursor, a carbenoid Fritsch-Buttenberg-Wiechell (FBW) rearrangement is used to gene

A one-pot synthesis and functionalization of polyynes

A one-pot synthesis and derivatization of diynes and triynes is reported. The polyyne framework is formed from a dibromoolefin precursor based on a carbenoid rearrangement, and the resulting Li-acetylide is then trapped in situ with an electrophile to pro