87966-80-1Relevant academic research and scientific papers
Process for the preparation of 1,4-dihydropyridine derivatives
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, (2008/06/13)
In the preparation of 1,4-dihydropyridine derivatives of formula (I), the improvement which comprises reacting a 2-haloethyl 2-benzylidene-3-oxobutanoate of formula (IV) with a 3-aminocrotonic acid ester of formula (V) in a reaction medium in the presence of a dehydrating agent. In the formulae R1, R2, R3 and X have the same meanings as defined in the claims.
