87974-30-9Relevant academic research and scientific papers
ASYMMETRIC HYDROGENATION WITH RHODIUM(I)-CHIRAL DIPHOSPHINITES. THE EFFECT OF THE DIMETHYLAMINO GROUP OF THE LIGAND ON THE ASYMMETRIC INDUCTION.
Yatagai,Zama,Yamagishi,Hida
, p. 739 - 746 (2007/10/02)
New chiral diphosphinites were prepared starting from ( plus )-diethyl tartrate. The asymmetric hydrogenation of dehydroamino acids, itaconic acid and dehydrodipeptides was studied using Rh(I)-diphosphinite catalysts. In the hydrogenation of dehydroamino acid derivatives, an introduction of omega -(dimethylamino)alkyl group in the ligands did not raise the optical yield. By the use of Rh(I)-diphosphinite having 3-(dimethylamino)propyl group the inversion of the preferred product was observed. 19 refs.
EFFECTIVE ASYMMETRIC HYDROGENATION OF DEHYDRODIPEPTIDES WITH RHODIUM(I)-NEW CHIRAL DIPHOSPHINITE SYSTEMS
Yatagai, Masanobu,Zama, Masanobu,Yamagishi, Takamichi,Hida, Mitsuhiko
, p. 1203 - 1206 (2007/10/02)
Rh(I)-new chiral diphosphinite systems with terminal amino groups were very effective for asymmetric hydrogenation of dehydrodipeptides with free carboxyl group and a chiral carbon.The effectiveness of the diphosphinite catalysts strongly suggests the contribution of electrostatic effect to asymmetric induction.
