87976-13-4

Basic information

• Product Name: 2,4-Imidazolidinedione, 5,5-dimethyl-1,3-diphenyl-
• CAS NO: 87976-13-4
• Molecular Formula: C17H16N2O2
• Molecular Weight: 280.326
• Mol File: 87976-13-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2,4-Imidazolidinedione, 5,5-dimethyl-1,3-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Imidazolidinedione, 5,5-dimethyl-1,3-diphenyl-(87976-13-4)
• EPA Substance Registry System: 2,4-Imidazolidinedione, 5,5-dimethyl-1,3-diphenyl-(87976-13-4)

Safety Data

• Hazardous Substances Data: 87976-13-4(Hazardous Substances Data)

Upstream product

• 103-71-9 phenyl isocyanate 
• 28873-61-2 5,5-dimethyl-5H-[1,3,4]oxadiazol-2-one 
• 87976-12-3 5,5-dimethyl-1,3-diphenyl-2-thioxoimidazolidin-4-one 
• 58109-40-3 diphenyliodonium hexafluorophosphate 
• 1483-73-4 diphenyliodonium bromide 
• 115298-63-0 phenyl(4-methoxyphenyl)iodonium triflate 
• 144930-50-7 mesityl(phenyl)iodonium triflouromethanesulfonate 
• 70974-10-6 5,5-dimethyl-3-phenylimidazolidine-2,4-dione 
• 66003-76-7 Diphenyliodonium triflate 
• 20059-64-7 ethyl 2-methyl-2-(phenylamino)propanoate 
• 582-61-6 benzoyl azide 
• 77-71-4 5,5-dimethyl-imidazolidine-2,4-dione 
• 591-50-4 iodobenzene 
• 2052-01-9 2-bromo-2-methylpropionic acid 

Downstream Products

• 87976-11-2 4,4-dimethyl-1,3-diphenyl-5-thioxoimidazolidin-2-one 

Relevant articles and documents

N1- and N3-Arylations of Hydantoins Employing Diaryliodonium Salts via Copper(I) Catalysis at Room Temperature

Copper(I)-catalyzed N-arylation (both N1- and N3-) of hydantoins with diaryliodonium salts as aryl partners at room temperature is reported. The transformation allows diverse scopes on both hydantoins and diaryliodonium salts deliver

Copper-Mediated N-Arylations of Hydantoins

A set of two broadly applicable procedures for the N-arylation of hydantoins is reported. The first one relies on the use of stoichiometric copper(I) oxide under ligand- A nd base-free conditions and enables a clean regioselective arylation at the N3 nitrogen atom, while the second one is based on the use of catalytic copper(I) iodide and trans-N,N′-dimethylcyclohexane-1,2-diamine and promotes arylation at the N1 nitrogen atom. Importantly, the combination of these two procedures affords a straightforward entry to diarylated hydantoins.

Synthesis of new imidazolidinones, spiro-imidazolidinones and spiro-hydantoins

α-Alkyl/aryl-α-arylaminopropionitriles (1) and 1-arylamino-1-cyano-cyclohexanes/cyclopentanes (5) react with alkyl/arylisocyanates to afford new imidazolidinones (2, 3) and spiro-imidazolidinones (6, 7) respectively. Compounds 2 and 6 on hydrolysis give hydantoins (4) and spiro-hydantoins (8), respectively.