880078-67-1

Basic information

• Product Name: (Z)-3-(4-chlorophenyl)-2,3-diphenylacrylic acid
• Synonyms: (Z)-3-(4-chlorophenyl)-2,3-diphenylacrylic acid
• CAS NO: 880078-67-1
• Molecular Weight: 334.802
• Mol File: 880078-67-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-3-(4-chlorophenyl)-2,3-diphenylacrylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-3-(4-chlorophenyl)-2,3-diphenylacrylic acid(880078-67-1)
• EPA Substance Registry System: (Z)-3-(4-chlorophenyl)-2,3-diphenylacrylic acid(880078-67-1)

Safety Data

• Hazardous Substances Data: 880078-67-1(Hazardous Substances Data)

Upstream product

• 20050-22-0 2t-bromo-1.2c-diphenyl-1r-(4-chloro-phenyl)-ethylene 
• 20050-23-1 (Z)-1-bromo-2-(4-chloro-phenyl)-1,2-diphenyl-ethene 
• 124-38-9 carbon dioxide 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 501-65-5 diphenyl acetylene 
• 1589-82-8 phenylmagnesium bromide 
• 84224-92-0 1-(4-chlorophenyl)-1,2-diphenylethanol 

Relevant articles and documents

Nickel-Catalyzed Arylative Carboxylation of Alkynes with Arylmagnesium Reagents and Carbon Dioxide Leading to Trisubstituted Acrylic Acids

Nickel-catalyzed arylcarboxylation of alkynes with arylmagnesium reagents and carbon dioxide (CO2, 1 atm) was realized in one pot. Various trisubstituted acrylic acids within an aryl group at the β-position have been prepared efficiently with good regioselectivity under mild conditions. The resulting products could be further transformed to benzoannelated cycles retaining CO2 as a one-carbon synthon.