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1-oxoeudesma-2,4-dien-11βH-12,6α-olide is a complex organic compound belonging to the class of eudesmane sesquiterpenoids, which are derived from the isoprene unit. This specific compound is characterized by a unique carbon skeleton with a 1-oxo (carbonyl) group, a 2,4-dien (two double bonds) system, and a 11βH-12,6α-olide (lactone) ring structure. The compound exhibits a diverse range of biological activities, including anti-inflammatory, antitumor, and antimicrobial properties, making it a potential candidate for pharmaceutical applications. Its chemical structure and functional groups contribute to its reactivity and interactions with various biological targets, highlighting the importance of understanding its properties for future drug development and therapeutic applications.

88010-70-2

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88010-70-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 88010-70-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,0,1 and 0 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 88010-70:
(7*8)+(6*8)+(5*0)+(4*1)+(3*0)+(2*7)+(1*0)=122
122 % 10 = 2
So 88010-70-2 is a valid CAS Registry Number.

88010-70-2Downstream Products

88010-70-2Relevant academic research and scientific papers

A short-step synthesis of sesquiterpene lactone, 1-oxoeudesma-2,4-dien-11βh-12, 6α-olide, isolated from artemisia herba-alba and its derivatives

Kawamata,Nagashima,Nakai,Tsuji

, p. 139 - 148 (1996)

1-Oxoeudesma-2,4-dien-11βH-12,6α-olide(1) isolated from the genus Artemisia herb-alba was synthesized from α-santonin in a two-step sequence. The key step is the 1,3 oxidative rearrangement of dienol 7.

SYNTHESIS, BIOTRANSFORMATION AND STEREOCHEMISTRY OF 6β-SESQUITERPENE LACTONES: SYNTHESES OF 6β-ARTEPAULIN, 11,13-DIHYDRO-6β-TUBERIFERIN, 5,15-DIHYDRO-6β-OOPODIN, 4-EPI-6β-VULGARIN AND 6β-VULGARIN

Amate, Yolanda,Breton, Jose L.,Garcia-Granados, Andres,Martinez, Antonio,Onorato, Esther,Buruaga, Antonio Saenz de

, p. 6939 - 6950 (2007/10/02)

6β-Artepaulin, 11,13-dihydro-6β-tuberiferin, 4,15-dihydro-6β-oopodin, 4-epi-6β-vulgarin and 6β-vulgarin were obtained from α-santonin.Stereochemical studies showed that the configuration at C-6 is decisive in the chemical behaviour of the A ring.Biotransformation of 1-oxo-5,6α,4,11βH-eudesm-2-en-6,12-olide with Rhizopus nigricans cultures probed to be a very efficient alternative way to obtain 4-epi-6β-vulgarin, which was then converted to 6β-vulgarin, a convenient starting material for biogenetical studies of pseudoguaianolides.A new 8β-hydroxyl derivative obtained from this biotransformation constitutes a new approach to the synthesis of 8,12-eudesmanolides and other sesquiterpenolides.Molecular structures were determined mainly by mono- and bidimensional nmr experiments.

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