A short-step synthesis of sesquiterpene lactone, 1-oxoeudesma-2,4-dien-11βh-12, 6α-olide, isolated from artemisia herba-alba and its derivatives

Article abstract of DOI:10.1080/00397919608003873

1-Oxoeudesma-2,4-dien-11βH-12,6α-olide(1) isolated from the genus Artemisia herb-alba was synthesized from α-santonin in a two-step sequence. The key step is the 1,3 oxidative rearrangement of dienol 7.

Full text of DOI:10.1080/00397919608003873

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A Short-Step Synthesis of
Sesquiterpene Lactone,
1-Oxoeudesma-2,4-
dien-11βH-12, 6α-Olide,
Isolated from Artemisia
Herba-Alba and its
Derivatives
T. Kawamata a , K. Nagashima a , R. Nakai a & T.
Tsuji b
a Pharmaceutical Institute, School of Medicine,
Keio University , Shinanomachi, Shinjuku-ku 35,
Tokyo, 160, Japan
b Faculty of Science, Department of Chemical
and Biological Sciences , Japan Women's
University , Mejirodai 2–8–1, Bunkyo-ku, Tokyo,
112, Japan
Published online: 21 Aug 2006.
To cite this article: T. Kawamata , K. Nagashima , R. Nakai & T. Tsuji (1996) A
Short-Step Synthesis of Sesquiterpene Lactone, 1-Oxoeudesma-2,4-dien-11βH-12,
6α-Olide, Isolated from Artemisia Herba-Alba and its Derivatives, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 26:1, 139-148, DOI: 10.1080/00397919608003873

To link to this article: http://dx.doi.org/10.1080/00397919608003873
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