880169-76-6

Upstream product

• 170899-08-8 N-(tert-butoxycarbonyl)-D-allylglycine 
• 72235-53-1 3,4-difluorobenzylamine 
• 880169-75-5 {1-[(3,4-difluorobenzylamino)-methyl]-but-3-enyl}-carbamic acid tert-butyl ester 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 880169-77-7 2-allyl-4-(3,4-difluorobenzyl)-2-naphthalen-2-ylmethyl-3-oxo-piperazine-1-carboxylic acid tert-butyl ester 
• 880169-79-9 C₄₁H₅₃F₂N₅O₇ 
• 880169-78-8 4-(3,4-difluorobenzyl)-6-(3-hydroxy-propyl)-2-naphthalen-2-ylmethyl-3-oxo-piperazine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Ketopiperazines: Conformationally constrained peptidomimetic of arginine amides

We have synthesized guanidine-containing ketopiperazines designed to be conformational mimics of peptidomimetic arginine amides. D-Allylglycine was converted by an efficient approach to give enantiopure ketopiperazines in which the trans stereochemistry o