88023-93-2Relevant academic research and scientific papers
An efficient synthesis of [1,3,4]thiadiazolo[2,3-c ][1,2,4] triazin-4-ones
Mohebat, Razieh,Tabatabaee, Masoumeh,Bafghi, Mohammad Ashrafi
, p. 377 - 382 (2013/09/23)
A three-component reaction between 4-amino-6-methyl-3-thioxo-3,4-dihydro- 2H-[1,2,4]triazin-5-one, ammonium thiocyanate and aroyl chlorides in the presence of N-methylimidazole to afford the [1,3,4]thiadiazolo[2,3-c][1,2,4] triazin-4-ones in excellent yields is described.
Synthesis of thiadiazolobenzamide, via cyclization of thioxothiourea, and its Ni and Pd complexes
Adhami, Forogh,Nabilzadeh, Nasim,Emmerling, Franziska,Ghiasi, Mina,Heravi, Majid M.
, p. 1211 - 1222,12 (2020/09/14)
In this study, a compound, N-(3-methyl-4-oxo-4H-[1,3,4]thiadiazolo[ 2,3-c][1,2,4]triazin-7-yl)benzamide, was obtained via two different reactions: 1) reaction of 4-amino-6-methyl-3-(methylthio)-1,2,4-triazin-5(4H)-one with benzoyl isothiocyanate under removal of methanethiol and 2) reaction of 4-amino-3,4-dihydro-6-methyl-3-thioxo-1,2,4-triazin-5(2H)-one with benzoyl isothiocyanate under elimination of hydrogen sulfide. In both reactions, a new bond between sulfur and nitrogen atoms was formed and a five-membered ring was created. The oxo thiadiazolo benzamide was characterized by IR, 1H-NMR and 13C-NMR spectroscopy, and mass spectrometry. X-Ray crystallography was used to shed light on the structure of this new compound. Two new complexes could be generated by coordination of the oxo thiadiazolo benzamide to Pd(II) and Ni(II) ions. These complexes were analyzed by IR, 1H-NMR and 13C NMR spectroscopy, conductometry and thermal gravimetry (TGA). The theoretical QM calculation GIAO was also applied to predict the structure of the Pd complex.
On the Preparation of Substituted 4H-1,3,4-Thiadiazolo[2,3-c]-1,2,4-triazin-4-ones and 1,2,4-Triazolo[3,4-b]-1,3,4-thiadiazoles
Coppo, Frank T.,Fawzi, Maged M.
, p. 1351 - 1354 (2007/10/03)
The reaction of benzoyl isothiocyanates and methoxycarbonyl isothiocyanate with 4-amino-4,5-dihydro-3-(methylthio)-1,2,4-triazin-5-ones in acetonitrile gave several substituted 4H-1,3,4-thiadiazolo[2,3-c]-1,2,4-triazin-4-ones VIa-h instead of the expected
