880359-08-0

Upstream product

• 24679-72-9 (2S,3S)-2,3-dimethoxy-1,4-butanediol 
• 100-39-0 benzyl bromide 
• 107291-10-1 (+)-(2S,3S)-4-(benzyloxy)-2,3-dimethoxy-1-butanol 

Downstream Products

• 880359-09-1 1-O-benzyl-4-deoxy-4-ethoxy(phenyl)phosphinoyl-2,3-di-O-methyl-L-threitol 
• 880359-11-5 1-bromo-1,4-dideoxy-4-ethoxy(phenyl)phosphinoyl-2,3-di-O-methyl-L-threitol 
• 880359-10-4 4-deoxy-4-ethoxy(phenyl)phosphinoyl-2,3-di-O-methyl-L-threitol 
• 115952-07-3 (3R,4R)-3,4-dimethoxy-1-phenylphospholane 

Relevant academic research and scientific papers

Synthesis of phospholane 1-oxide having oxygen functional groups from a 4-bromobutylphoshinate derivative

Ethyl 4-bromo-2,3-dimethoxybutyl(phenyl)phosphinate (10a) was prepared from 2,3-di-O-methyl-L-threitol (12) in five steps. Reduction of 10a with sodium dihydrobis(2-methoxyethoxy)aluminate, followed by the action of hydrogen peroxide, afforded 3,4-dimetho