88036-24-2

Upstream product

• 88036-23-1 5-<2-<2-(4-hydroxyphenyl)-1(S)-<<(2,2,2-trichloroethoxy)carbonyl>amino>ethyl>-1,3-dioxolan-2-yl>-3-oxopentanoyl-L-phenylalanyl-L-leucine 
• 88036-17-3 2-<2-<4-(benzyloxy)phenyl>-1(S)-phthalimidoethyl>-2-(3-oxopropyl)-1,3-dioxolane 
• 88036-19-5 2-<1(S)-amino-2-<4-(benzyloxy)phenyl>ethyl>-2-<5-(1,3-dioxolan-2-yl)-3-hydroxypentyl>-1,3-dioxolane 
• 88036-21-9 5-<2-<2-<4-(benzyloxy)phenyl>-1(S)-<<(2,2,2-trichloroethyloxy)carbonyl>amino>ethyl>-1,3-dioxolan-2-yl>-3-oxopentanoyl-L-phenylalanyl-L-leucine methyl ester 
• 88036-22-0 5-<2-<2-<4-(benzyloxy)phenyl>-1(S)-<<(2,2,2-trichloroethoxy)carbonyl>amino>ethyl>-1,3-dioxolan-2-yl>-3-oxopentanoyl-L-phenylalanyl-L-leucine 
• 88036-18-4 2-<2-<4-(benzyloxy)phenyl>-1(S)-phthalimidoethyl>-2-<5-(1,3-dioxolan-2-yl)-3-hydroxypentyl>-1,3-dioxolane 
• 88036-20-8 2-<2-<4-(benzyloxy)phenyl>-1(S)-<<(2,2,2-trichloroethoxy)carbonyl>amino>ethyl>-2-(5-carboxy-5-oxopentyl)-1,3-dioxolane 
• 88036-16-2 2-<2-<4-(benzyloxy)phenyl>-1(S)-phthalimidoethyl>-2-<2-(1,3-dioxolan-2-yl)ethyl>-1,3-dioxolane 
• 88036-15-1 2-<5-<4-(benzyloxy)phenyl>-3-oxo-4(S)-phthalimidopentyl>-1,3-dioxolane 
• 88036-14-0 (S)-N^α-phthaloyl-O-benzyltyrosine chloride 
• 2130-97-4 (S)-N^α-phthaloyl-O-benzyltyrosine 

Downstream Products

• 88036-25-3 8(S)-amino-4,7-dioxo-9-(4-hydroxyphenyl)nonanoyl-L-phenylalanyl-L-leucine 

Relevant academic research and scientific papers

Replacement of the peptide-backbone amides connecting Tyr-Gly and Gly-Gly in leucine-enkephalin with ketomethylene groups: Synthesis and biological activity

A peptide analogue of Leu-enkephalin was synthesized in which the amide linkages between Tyr-Gly and Gly-Gly were replaced by ketomethylene groups. The resulting analogue, x, had 1/4000th and 1/2400th the opiate receptor binding activity of Leu-enkephalin