88041-83-2Relevant academic research and scientific papers
CYTOKINE INHIBITORS
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Page/Page column 119-120, (2008/12/07)
The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions mediated by cytokines, such as for example arthritis, pain, cardiovascular disease and cancer.
A convenient synthesis of 2-hydroxybenzenesulfonamide
Drygala,Kirby,Watson
, p. 671 - 675 (2007/10/02)
Chlorosulfonation of 4-t-butylanisole and formation of the sulfonamide 2, followed by removal of the t-butyl and O-methyl groups with aluminium chloride provides a simple, novel synthesis of 2-hydroxybenzenesulfonamide 3.
6-sulfoxyphenol derivatives, their preparation and their use as cytoprotective agents
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, (2008/06/13)
Compounds of the formula I STR1 where R1 is hydrogen, lower alkyl, lower alkoxy, amino or dialkylamino; R2 and R3 are O-alkyl, N-dialkyl or S-alkyl, or R2 and R3 together represent --X--(CH2/sub
2-aminomethyl-6-sulfamoylphenol derivatives, a process for their preparation and their use and also pharmaceutical formulations based on these compounds
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, (2008/06/13)
The invention relates to 2-aminomethylphenols of the formula I STR1 in which R1 and R2 represent hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl or benzyl which is optionally substituted by alkyl, alkoxy or halogen, R3 and R
