3724-14-9

Usage

Uses

Used in Pharmaceutical Industry:
Benzenesulfonamide, 2-hydroxy(9CI) is used as a pharmaceutical intermediate for the synthesis of various drugs and other organic compounds. Its unique structure allows it to be a key component in the development of new medications, contributing to the advancement of pharmaceutical research and drug discovery.
Used in Dye and Pigment Production:
In the chemical industry, Benzenesulfonamide, 2-hydroxy(9CI) is utilized in the production of dyes and pigments. Its chemical properties make it suitable for creating a variety of colorants used in different applications, such as textiles, plastics, and printing inks, enhancing the color quality and performance of these products.
Used in Organic Synthesis:
As a versatile building block in organic synthesis, Benzenesulfonamide, 2-hydroxy(9CI) is employed in the creation of various organic compounds for different industries. Its unique structure allows for further chemical reactions and modifications, making it a valuable precursor in the synthesis of specialty chemicals, agrochemicals, and other fine chemicals.

Upstream product

• 39082-29-6 2-benzyloxy-benzenesulfonic acid amide 
• 5396-38-3 1-(tert-butyl)-4-methoxybenzene 
• 1189-71-5 isocyanate de chlorosulfonyle 
• 60-29-7 diethyl ether 
• 108-95-2 phenol 
• 17176-77-1 Dibenzyl phosphite 
• 108-48-5 2,6-dimethylpyridine 
• 52960-57-3 2-methoxyphenylsulfonamide 
• 88041-83-2 3-(1,1-dimethylethyl)-6-methoxybenzenesulfonyl chloride 
• 88085-79-4 5-tert-butyl-2-methoxy-benzenesulfonamide 

Downstream Products

• 99060-98-7 (2-acetoxy-benzenesulfonyl)-acetyl-amine 
• 100394-32-9 2-(toluene-4-sulfonyloxy)-benzenesulfonic acid amide 
• 19801-65-1 N-cyclohexylcarbamoyl-2-hydroxy-benzenesulfonamide 
• 19801-63-9 N-(2-hydroxy-benzenesulfonyl)-formimidic acid ethyl ester 
• 19801-50-4 3-benzyl-benzo[1,4,3]oxathiazine 1,1-dioxide 
• 152531-37-8 2-(2-Chloro-1,1,2-trifluoroethoxy)-benzenesulfonamide 
• 138681-78-4 2-allyloxy-benzenesulphonamide 
• 17176-77-1 Dibenzyl phosphite 
• 58734-61-5 2-ethoxybenzene-1-sulfonamide 
• 2310-89-6 phenyl hydrogen phosphonate 

Relevant academic research and scientific papers

A convenient synthesis of 2-hydroxybenzenesulfonamide

Chlorosulfonation of 4-t-butylanisole and formation of the sulfonamide 2, followed by removal of the t-butyl and O-methyl groups with aluminium chloride provides a simple, novel synthesis of 2-hydroxybenzenesulfonamide 3.

Method for catalytic synthesis of N-benzyl benzene sulfonamide compounds by boric acid/oxalic acid catalytic system under microwave radiation

The invention discloses a method for catalytic synthesis of N-benzyl benzene sulfonamide compounds by a boric acid/oxalic acid catalytic system under microwave radiation. The method includes: adoptingbenzyl alcohol and derivatives thereof and benzene sulfonamide derivatives as raw materials, adopting the boric acid/oxalic acid system as a catalyst, and adopting fluorobenzene as a solvent; performing reaction in a microwave reactor under certain temperature and power conditions, performing vacuum concentration after reaction for a period of time, and subjecting a product to column chromatographic purification to realize efficient catalytic preparation of the N-benzyl benzene sulfonamide compounds. Compared with the prior art, the method has advantages of evidently higher reaction speed than that of conventional heating, mild reaction conditions, simplicity in operation, high yield, safety, low cost and environmental friendliness.

NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION

The embodiments provide compounds of the general Formulae I, II, III, IV, V, VI, VII, and X, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.

Method and compositions for identifying anti-HIV therapeutic compounds

Methods are provided for identifying anti-HIV therapeutic compounds substituted with carboxyl ester or phosphonate ester groups. Libraries of such compounds are screened optionally using the novel enzyme GS-7340 Ester Hydrolase. Compositions and methods relating to GS-7340 Ester Hydrolase also are provided.

Method and compositions for identifying anti-HIV therapeutic compounds

Methods are provided for identifying anti-HIV therapeutic compounds substituted with carboxyl ester or phosphonate ester groups. Libraries of such compounds are screened optionally using the novel enzyme GS-7340 Ester Hydrolase. Compositions and methods relating to GS-7340 Ester Hydrolase also are provided.

ARYL THIOPYRANO[2,3,4-C,D]INDOLES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS

Compounds having the formula I: are inhibitors of 5-lipoxygenase and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cyto-protective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, psoriasis, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.

N-Phenylsulfonyl-N'-pyrimidinylureas

N-Phenylsulfonyl-N'-pyrimidinyl ureas of the formula STR1 and the salts thereof with amines, alkali metal or alkaline earth metal bases or with quaternary ammonium bases, have good pre- and postemergence selective herbicidal and growth regulating properti

N-Phenylsulfonyl-N'-triazinylureas

N-Phenylsulfonyl-N'-triazinyl-ureas of the formula STR1 and the salts thereof with amines, alkali metal or alkaline earth metal bases or with quaternary ammonium bases, have good pre- and postemergence selective herbicidal and growth regulating properties

N-Phenylsulfonyl-N'-triazinylureas

N-Phenylsulfonyl-N'-triazinylureas of the general formula STR1 and the salts thereof with amines, alkali metal or alkaline earth metal bases or with quaternary ammonium bases, have good pre- and postemergence selective herbicidal and growth regulating pro

N-Phenylsulfonyl-N'-pyrimidinylureas

N-Phenylsulfonyl-N'-pyrimidinylureas of the general formula STR1 and the salts thereof with amines, alkali metal or alkaline earth metal bases or with quaternary ammonium bases, have good pre- and postemergence selective herbicidal and growth regulating p