88091-66-1

Basic information

• Product Name: 1-(p-nitrophenylethoxycarbonyl)-benzotriazole
• Synonyms: 1-(p-nitrophenylethoxycarbonyl)-benzotriazole
• CAS NO: 88091-66-1
• Molecular Weight: 312.285
• Mol File: 88091-66-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(p-nitrophenylethoxycarbonyl)-benzotriazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(p-nitrophenylethoxycarbonyl)-benzotriazole(88091-66-1)
• EPA Substance Registry System: 1-(p-nitrophenylethoxycarbonyl)-benzotriazole(88091-66-1)

Safety Data

• Hazardous Substances Data: 88091-66-1(Hazardous Substances Data)

Upstream product

• 100-27-6 2-(4-nitrophenyl)ethanol 
• 65095-13-8 1-benzotriazolecarboxylic acid chloride 

Downstream Products

• 88091-67-2 2'-deoxy-N⁴-{[2-(4-nitrophenyl)ethoxy]carbonyl}cytidine 
• 91592-92-6 5'-O-monomethoxytrityl-N⁴-p-nitrophenylethoxycarbonyl-2'-deoxycytidine-3'-(2,5-dichlorophenyl,p-nitrophenylethyl)-phosphate 
• 91592-93-7 N⁴-p-nitrophenylethoxycarbonyl-2'-deoxycytidine-3'-(2,5-dichlorophenyl,p-nitrophenylethyl)-phosphate 
• 91592-91-5 2'-deoxy-5'-O-(4-monomethoxytrityl)-N⁶-[2-(4-nitrophenyl)ethoxycarbonyl]cytidine 
• 91592-95-9 triethylammonium 5'-O-monomethoxytrityl-N⁴-p-nitrophenylethoxycarbonyl-2'-deoxycytidine-3'-p-nitrophenylethyl-phosphate 
• 88121-72-6 N⁴-<2-(4-nitrophenyl)ethoxycarbonyl>cytidine 

Relevant articles and documents

THE USE OF THE p-NITROPHENYLETHOXYCARBONYL GROUP FOR AMINO PROTECTION IN CYTIDINE AND ADENOSINE CHEMISTRY

Amino protection in 2'-deoxycytidine (1) and cytidine (2) as well as in 2'-deoxyadenosine (8) and adenosine (9) respectively can be achieved by the new reagents 1-(p-nitrophenylethoxycarbonyl)-benzotriazole (3) and 1-methyl-3-(p-nitrophenylethoxycarbonyl)-imidazolium chloride (7) to from the corresponding carbamates (4, 5, 13, 14) in high yields.