THE USE OF THE p-NITROPHENYLETHOXYCARBONYL GROUP FOR AMINO PROTECTION IN CYTIDINE AND ADENOSINE CHEMISTRY

DOI: 10.1016/S0040-4039(00)88174-5

Source and publish data:

Tetrahedron Letters p. 3583 - 3586 (1983)

Update date:2022-08-04

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Authors:

Himmelsbach, Frank

Pfleiderer, Wolfgang

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Article abstract of DOI:10.1016/S0040-4039(00)88174-5

Amino protection in 2'-deoxycytidine (1) and cytidine (2) as well as in 2'-deoxyadenosine (8) and adenosine (9) respectively can be achieved by the new reagents 1-(p-nitrophenylethoxycarbonyl)-benzotriazole (3) and 1-methyl-3-(p-nitrophenylethoxycarbonyl)-imidazolium chloride (7) to from the corresponding carbamates (4, 5, 13, 14) in high yields.

Full text of DOI:10.1016/S0040-4039(00)88174-5

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