88107-02-2

Upstream product

• 64283-87-0 4-phenyl-1-iodobutane 
• 3360-41-6 4-phenyl-butan-1-ol 
• 13633-25-5 1-Bromo-4-phenylbutane 
• 62607-64-1 4-phenyl-butane-1-sulfonic acid 
• 116956-35-5 sodium 4-phenylbutane-1-sulfonate 
• 408351-76-8 bis(4-phenylbutyl) disulfide 

Downstream Products

• 80639-69-6 4-phenyl-1-butanesulphonyl azide 
• 1404225-72-4 4-phenylbutane-1-sulfonyl fluoride 

Relevant academic research and scientific papers

Enantioselective Radical Construction of 5-Membered Cyclic Sulfonamides by Metalloradical C-H Amination

Both arylsulfonyl and alkylsulfonyl azides can be effectively activated by the cobalt(II) complexes of D2-symmetric chiral amidoporphyrins for enantioselective radical 1,5-C-H amination to stereoselectively construct 5-membered cyclic sulfonami

Sulfonyl fluoride inhibitors of fatty acid amide hydrolase

Sulfonyl fluorides are known to inhibit esterases. Early work from our laboratory has identified hexadecyl sulfonylfluoride (AM374) as a potent in vitro and in vivo inhibitor of fatty acid amide hydrolase (FAAH). We now report on later generation sulfonyl

Microwave-assisted synthesis of sodium sulfonates precursors of sulfonyl chlorides and fluorides

We describe the use of a microwave reaction for the conversion of various bromides to sodium sulfonates that have been further elaborated to sulfonyl chlorides. This new approach leads to much improved yields and shorter reaction times. Representative sul

COMPOUNDS AND METHODS FOR CONTROLLING BACTERIAL VIRULENCE

Novel sulfonated homoserine lactones formula I have been found to act ac quorum sensing inhibitors. As such, they may be useful in the treatment of bacterial infections.

Beta lactam compounds and their use as inhibitors of tryptase

Compounds of the formulas: are disclosed. These compounds inhibit tryptase as well as other enzyme systems or are selective tryptase inhibitors and are useful as antiinflammatory agents particularly in the treatment of chronic asthma.