3360-41-6 Usage
Chemical Properties
colourless liquid
Uses
Different sources of media describe the Uses of 3360-41-6 differently. You can refer to the following data:
1. 4-Phenyl-1-butanol is used as a reagent in the synthesis of substituted pyrrolidine-2-carboxylic acids which are used in the treatment of AT2 receptor function associated diseases.
2. 4-Phenyl-1-butanol was used in synthesis of NK105, a paclitaxel-incorporating micellar nanoparticle formulation.
Synthesis Reference(s)
Chemical and Pharmaceutical Bulletin, 31, p. 2607, 1983 DOI: 10.1248/cpb.31.2607Journal of the American Chemical Society, 73, p. 124, 1951 DOI: 10.1021/ja01145a045
General Description
4-Phenyl-1-butanol is oxidized by ceric ammonium nitrate in acetonitrile to afford 2-phenyltetrahydrofuran. It undergoes cyclization in presence of phosphoric acid at high temperature to yield tetralin.
Check Digit Verification of cas no
The CAS Registry Mumber 3360-41-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,6 and 0 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3360-41:
(6*3)+(5*3)+(4*6)+(3*0)+(2*4)+(1*1)=66
66 % 10 = 6
So 3360-41-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H14O/c11-9-5-4-8-10-6-2-1-3-7-10/h1-3,6-7,11H,4-5,8-9H2
3360-41-6Relevant articles and documents
Young,Trahanovsky
, p. 5060,5062 (1969)
Selective hydroboration of equilibrating allylic azides
Liu, Ruzhang,Xu, Jun,Zhang, Yuanyuan
supporting information, p. 8913 - 8916 (2021/09/13)
The iridium(i)-catalyzed hydroboration of equilibrating allylic azides is reported to provide only the anti-Markovnikov product of alk-1-ene isomers in good yields and with good functional group tolerance.
Redox-active ligand based Mn(i)-catalyst for hydrosilylative ester reduction
Chakraborty, Soumi,Das, Arpan,Mandal, Swadhin K.
supporting information, p. 12671 - 12674 (2021/12/04)
Herein a Mn(i) catalyst bearing a redox-active phenalenyl (PLY) based ligand is reported for the efficient hydrosilylation of esters to alcohols using the inexpensive silane source polymethylhydrosiloxane (PMHS) under mild conditions. Mechanistic investigations suggest a strong ligand-metal cooperation where a ligand-based single electron transfer (SET) process initiates the reaction through Si-H bond activation.