88134-91-2

Upstream product

• 765-43-5 Cyclopropyl methyl ketone 
• 67435-25-0 1-aminooxy-3-[(1,1-dimethyl-ethyl)-amino]-2-hydroxy-propane 
• 88135-05-1 1-Cyclopropyl-ethanone O-oxiranylmethyl-oxime 
• 75-64-9 tert-butylamine 
• 51761-72-9 cyclopropyl methyl ketone oxime 

Downstream Products

• 106347-99-3 -1 cyclopropyl-1 ethane 
• 106348-01-0 -1 cyclopropyl-1 ethane 
• 106348-00-9 -1 cyclopropyl-1 ethane 
• 106348-07-6 benzyloxy-2-(N-t-butyl-N-t-butylaminoacetyl)amino-3 propanol-1 

Relevant academic research and scientific papers

New chiral and isomeric cyclopropyl ketoxime propanolamine derivatives with potent β-adrenergic blocking properties

The synthesis of R-(+) and s-(-)isomers of O-[3-(tert-butylamino)-2-hydroxypropyl] cyclopropyl methyl ketone oxime (falintolol) is described. The syn and anti isomers of falintolol were obtained in two different ways from cyclopropyl methyl ketoxime or from falintolol. For comparison purposes, the enantiomers of the dicyclopropyl ketone oxime derivatives were also prepared. Structure-activity relationships are described.

Synthesis and β-Adrenergic Blocking Activity of New Aliphatic and Alicyclic Oxime Ethers

We describe the synthesis and pharmacological properties of two new series of aliphatic and alicyclic β-adrenergic blockers, most of them containing a cyclopropyl ring.They belong either to 2-hydroxy-3-(tert-butylamino)propyl ether A or 2-hydroxy-3-tert-(