88135-31-3

Usage

Uses

Used in Pharmaceutical Industry:
(2,6-dichloro-4-nitro-phenyl)-acetic acid is used as an intermediate in the synthesis of pharmaceuticals for its reactivity and versatility in chemical reactions.
Used in Agrochemical Industry:
(2,6-dichloro-4-nitro-phenyl)-acetic acid is used as an intermediate in the production of agrochemicals, contributing to the development of effective pesticides and other agricultural products.
Used in Dye and Pigment Industry:
(2,6-dichloro-4-nitro-phenyl)-acetic acid is used as an intermediate in the production of dyes and pigments, enabling the creation of a variety of colorants for different applications.
Used in Organic Compounds Synthesis:
(2,6-dichloro-4-nitro-phenyl)-acetic acid is used as a versatile intermediate in the synthesis of other organic compounds, taking advantage of its reactivity to form new chemical entities for various purposes.

Upstream product

• 20098-48-0 3,4,5-trichloronitrobenzen 
• 105-53-3 diethyl malonate 
• 2112-17-6 2,6-dichloro-4-nitrobenzonitrile 
• 88135-30-2 2-(2,6-dichloro-4-nitrophenyl)acetonitrile 
• 618-62-2 3,5-dichloro-1-nitrobenzene 

Downstream Products

• 315227-97-5 5-Chloro-2-(2,6-dichloro-4-nitro-benzyl)-benzothiazole 
• 88135-25-5 methyl 2-(2,6-dichloro-4-nitrophenyl)acetate 

Relevant academic research and scientific papers

ROR NUCLEAR RECEPTOR MODULATORS

The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological conditions.

Therapeutic modulation of PPARgamma activity

Modulators of PPARγ activity are used in methods of treating and/or preventing conditions such as osteoporosis, Alzheimer's disease, psoriasis and acne, and cancer.

COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, BCR-Abl, CSK, JNK1, JNK2, PDGF-R, p38, p70S6K, TGF beta , SRC, EGFR, c-Kit, trkB, FGFR3, Fes, Lck, Syk, RAF, MKK4, MKK6 and SAPK2 beta kinases.

Compounds for the modulation of PPARgamma activity

Modulators of PPARγ activity are provided which are useful in pharmaceutical compositions and methods for the treatment of conditions such as type II diabetes and obesity.

Benzylideneamino- and phenylacetylguanidines and their pharmaceutical uses

Compounds of formula (I): STR1 or a salt or acyl derivative thereof; wherein Y is either --CH=N or STR2 R1 is hydroxy, halogen, (C1-4) alkyl, or (C1-4)alkoxy, R2 is a nitrogen-containing, basic substituent, R3 is hydrogen, hydroxy, halogen, (C1-4) alkyl, (C1-4) alkoxy or a nitrogen-containing, basic substituent, and R4 is hydrogen or hydroxy, are useful in treating diarrhoea and scours.