88140-01-6

Upstream product

• 88139-96-2 (3S^*,4R^*)-1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-3-<(R^*)-1-(o-nitrobenzyloxycarbonyloxy)ethyl>-4-<2-t-butyldimethylsilyloxymethyl-5'-pyridylcarbonyl>methyl-azetidin-2-one 
• 88198-13-4 {(2R,3S)-2-Carboxymethyl-3-[(R)-1-(2-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid 2-nitro-benzyl ester 
• 88139-89-3 (3S^*,4R^*)-1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-3-<(R^*)-1-(o-nitrobenzyloxycarbonyloxy)ethyl>-4-(2-pyridylthiocarbonyl)methyl-azetidin-2-one 
• 88198-12-3 {(2R,3S)-2-(2-Hydroxy-ethyl)-3-[(R)-1-(2-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid 2-nitro-benzyl ester 
• 88139-92-8 2-<<(tert-butyldimethylsilyl)oxy>methyl>-5-bromopyridine 
• 88139-91-7 (5-bromopyridin-2-yl)methanol 

Relevant academic research and scientific papers

Total synthesis of thienamycin analogs - III. Synthesis of 2-aryl and 2-heteroaryl analogs of theinamycin

The total syntheses of 2-aryl and 2-heteroaryl carbapen-2-em-3-carboxylic acids with and without a 6-hydroxyethyl side chain, using Wittig cyclization for formation of the bicyclic ring system is described. Antibacterial activity of the compounds synthesized is discussed.