88198-13-4

Upstream product

• 88198-12-3 {(2R,3S)-2-(2-Hydroxy-ethyl)-3-[(R)-1-(2-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid 2-nitro-benzyl ester 

Downstream Products

• 88139-89-3 (3S^*,4R^*)-1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-3-<(R^*)-1-(o-nitrobenzyloxycarbonyloxy)ethyl>-4-(2-pyridylthiocarbonyl)methyl-azetidin-2-one 
• 88139-94-0 (3S^*,4R^*)-1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-3-<(R^*)-1-(o-nitrobenzyloxycarbonyloxy)ethyl>-4-(2'-t-butyldimethylsilyloxymethyl-5'-thienylcarbonyl)methyl-azetidin-2-one 
• 88139-97-3 (3S^*,4R^*)-1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-3-<(R^*)-1-(o-nitrobenzyloxycarbonyloxy)ethyl>-4-(2'-t-butyldimethylsilyloxymethyl-5'-furanylcarbonyl)methyl-azetidin-2-one 
• 88139-96-2 (3S^*,4R^*)-1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-3-<(R^*)-1-(o-nitrobenzyloxycarbonyloxy)ethyl>-4-<2-t-butyldimethylsilyloxymethyl-5'-pyridylcarbonyl>methyl-azetidin-2-one 
• 88139-95-1 (3S^*,4R^*)-1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-3-<(R^*)-1-(o-nitrobenzyloxycarbonyloxy)ethyl>-4-<4'-(2-t-butyldimethylsilyloxyethyl)phenylcarbonyl>methyl-azetidin-2-one 
• 88139-98-4 (3S^*,4R^*)-1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-3-<(R^*)-1-(o-nitrobenzyloxycarbonyloxy)ethyl>-4-<4'-(2-pyranyloxymethyl)phenylcarbonyl>methyl-azetidin-2-one 
• 88140-04-9 (3S^*,4R^*)-1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-3-<(R^*)-1-(o-nitrobenzyloxycarbonyloxy)ethyl>-4-(4'-methylsulfonyloxymethylphenylcarbonyl)methyl-azetidin-2-one 
• 88140-05-0 (3S^*,4R^*)-1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-3-<(R^*)-1-(o-nitrobenzyloxycarbonyloxy)ethyl>-4-(2'-methylsulfonyloxymethyl-5'-furanylcarbonyl)methyl-azetidin-2-one 
• 88140-23-2 (3S^*,4R^*)-1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-3-<(R^*)-1-(o-nitrobenzyloxycarbonyloxy)ethyl>-4-<4'-(N-methylamidomethyl)phenylcarbonylmethyl>-azetidin-2-one 
• 88140-22-1 (3S^*,4R^*)-1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-3-<(R^*)-1-(o-nitrobenzyloxycarbonyloxy)ethyl>-4-(4'-carboxymethylphenyl)carbonylmethyl-azetidin-2-one 
• 88140-00-5 (3S^*,4R^*)-1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-3-<(R^*)-1-(o-nitrobenzyloxycarbonyloxy)ethyl>-4-(4'-2-hydroxyethylphenyl)carbonylmethyl-azetidin-2-one 
• 88140-01-6 (3S^*,4R^*)-1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-3-<(R^*)-1-(o-nitrobenzyloxycarbonyloxy)ethyl>-4-(2'-hydroxymethyl-5'-pyridylcarbonyl)methyl-azetidin-2-one 
• 88139-99-5 (3S^*,4R^*)-1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-3-<(R^*)-1-(o-nitrobenzyloxycarbonyloxy)ethyl>-4-(2'-hydroxymethyl-5-thienylcarbonyl)methyl-azetidin-2-one 
• 88140-02-7 (3S^*,4R^*)-1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-3-<(R^*)-1-(o-nitrobenzyloxycarbonyloxy)ethyl>-4-(2-hydroxymethyl-5'-furanylcarbonyl)methyl-azetidin-2-one 

Relevant academic research and scientific papers

Total synthesis of thienamycin analogs - III. Synthesis of 2-aryl and 2-heteroaryl analogs of theinamycin

The total syntheses of 2-aryl and 2-heteroaryl carbapen-2-em-3-carboxylic acids with and without a 6-hydroxyethyl side chain, using Wittig cyclization for formation of the bicyclic ring system is described. Antibacterial activity of the compounds synthesized is discussed.