881402-16-0

Basic information

• Product Name: 6-(TRIFLUOROMETHYL)PYRIDINE-2-BORONIC ACID PINACOL ESTER
• Synonyms: 6-(TRIFLUOROMETHYL)PYRIDINE-2-BORONIC ACID PINACOL ESTER;2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine;3-hydroxy-2,3-dimethylbutan-2-yl hydrogen (6-(trifluoromethyl)pyridin-2-yl)boronate
• CAS NO: 881402-16-0
• Molecular Formula: C₁₂H₁₅BF₃NO₂
• Molecular Weight: 273.06
• Mol File: 881402-16-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6-(TRIFLUOROMETHYL)PYRIDINE-2-BORONIC ACID PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(TRIFLUOROMETHYL)PYRIDINE-2-BORONIC ACID PINACOL ESTER(881402-16-0)
• EPA Substance Registry System: 6-(TRIFLUOROMETHYL)PYRIDINE-2-BORONIC ACID PINACOL ESTER(881402-16-0)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• Hazardous Substances Data: 881402-16-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Development:
6-(TRIFLUOROMETHYL)PYRIDINE-2-BORONIC ACID PINACOL ESTER is used as a key intermediate in the synthesis of pharmaceuticals for its ability to form carbon-carbon or carbon-heteroatom bonds through cross-coupling reactions, contributing to the creation of complex molecular structures.
Used in Agrochemical Production:
In the agrochemical industry, 6-(TRIFLUOROMETHYL)PYRIDINE-2-BORONIC ACID PINACOL ESTER is used as a reagent in the synthesis of various agrochemicals, enabling the development of new compounds with improved properties for agricultural applications.
Used in Materials Science:
6-(TRIFLUOROMETHYL)PYRIDINE-2-BORONIC ACID PINACOL ESTER is employed as a building block in materials science for the synthesis of new materials with specific properties, such as enhanced stability or reactivity, through cross-coupling reactions.
Used in Organic Chemistry Research:
6-(TRIFLUOROMETHYL)PYRIDINE-2-BORONIC ACID PINACOL ESTER is used as a valuable tool in organic chemistry research for the construction of complex molecules, facilitating the development of novel compounds and advancing the understanding of chemical reactions and mechanisms.

Upstream product

• 73183-34-3 bis(pinacol)diborane 
• 189278-27-1 2-bromo-6-(trifluoromethyl)pyridine 

Downstream Products

• 1145683-05-1 4-Methyl-2-[4'-trifluoromethyl-5-(6-trifluoromethyl-pyridin-2-yl)-biphenyl-3-yl]-pentanoic acid ethyl ester 
• 1101205-39-3 2-biphenyl-4-yl-6-(trifluoromethyl)pyridine 
• 1096689-50-7 2-(p-tolyl)-6-(trifluoromethyl)pyridine 
• 1096689-54-1 C₁₃H₇F₆N 
• 1442120-80-0 4-methyl-N-(2,2,2-trifluoroethyl)-2-[(1-{4-[6-(trifluoromethyl)pyridin-2-yl]benzoyl}piperidin-4-yl)methyl]-2H-indazole-5-carboxamide 
• 1442121-20-1 N-(2-methoxyethyl)-4-methyl-2-[(1-{4-[6-(trifluoromethyl)pyridin-2-yl]benzoyl}piperidin-4-yl)methyl]-2H-indazole-5-carboxamide 

Relevant articles and documents

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The invention relates generally to compounds of formula (I) that modulate the activity of TGFβR-l and TGFβR-2, pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.