881423-75-2

Upstream product

• 108-36-1 1,3-dibromobenzene 
• 130222-84-3 5-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-D-ribono-1,4-lactone 

Downstream Products

• 881424-07-3 acetic acid 5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-6a-(3-bromo-phenyl)-2-(tert-butyl-diphenyl-silanyloxymethyl)-hexahydro-furo[3,2-b]furan-3-yl ester 
• 881423-98-9 acetic acid 6a-(3-bromo-phenyl)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-hexahydro-furo[3,2-b]furan-3-yl ester 
• 881423-79-6 (1R,5S,7R,8R)-5-(3-bromophenyl)-7-[(tert-butyldiphenylsilyloxy)methyl]-2,6-dioxabicyclo[3.3.0]octane-3,8-diyl diacetate 
• 881423-99-0 1-[(1R,3S,5S,7R,8R)-5-(3-bromophenyl)-8-hydroxy-7-(hydroxymethyl)-2,6-dioxabicyclo[3.3.0]octan-3-yl]thymine 

Relevant academic research and scientific papers

From intriguing reactivity of 2-bromothiophene to the first synthesis of C1′-disubstituted C-nucleosides

A two-step approach to a family of C1′-disubstituted C-nucleosides is described. It relies on a double aryl condensation on ribonolactone 1 to give the desired disubstituted diols 2c, 6c and 7c. The cycloetherification of these diols followed by protectin

Effects of halogenated WNA derivatives on sequence dependency for expansion of recognition sequences in non-natural-type triplexes

Triplex-forming oligonucleotides (TFOs) are sequence-specific DNA-binding agents, but their target duplexes are limited to homopurine/homopyrimidine sequences because of interruption of the pyrimidines bases in the purine region. This problem has not been