88150-22-5Relevant academic research and scientific papers
Synthesis and pharmacological characterisation of a conformationally restrained series of indole-2-carboxylates as in vivo potent glycine antagonists
Di Fabio, Romano,Araldi, Gianluca,Baraldi, Davide,Cugola, Alfredo,Donati, Daniele,Gastaldi, Paola,Giacobbe, Simone A,Micheli, Fabrizio,Pentassuglia, Giorgio
, p. 791 - 798 (2007/10/03)
After the identification of GV150526, the indole-2-carboxylate template was further explored in order to identify novel potential anti-stroke agents. In particular, the SAR of the side chain present at the C-3 position of the indole nucleus was widely stu
Process for producing indoles unsubstituted in the 2,3-position and N(3-chloropropionyl)indole produced thereby
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, (2008/06/13)
Indoles of the formula I which are unsubstituted in the 2- and 3-positions: STR1 wherein Z is hydrogen or a group --COR, and X and Y have the meanings defined in claim 1, can be produced by a novel, simple and economical process which comprises reacting a
