88157-41-9Relevant academic research and scientific papers
SUBSTITUTED TRICYCLICS AND METHOD OF USE
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Paragraph 1359, (2017/02/09)
The present invention provides for compounds of formula (I) wherein X, Y, and R1 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions mediated and modulated by CFTR, including cystic fibrosis, Sj?gren's syndrome, pancreatic insufficiency, chronic obstructive lung disease, and chronic obstructive airway disease. Also provided are pharmaceutical compositions comprised of one or more compounds of formula (I).
COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR
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Paragraph 0342, (2017/02/24)
Compounds of Formula (I) or a pharmaceutically acceptable salt, a solvate, a tautomer, an isomer or a deuterated analog thereof, wherein A, J, R1, R2, R3, R4, R5, R6, R7, R9, X, m and n are as described herein, compositions thereof, and methods and uses thereof.
CYCLOPROPYLAMINES AS LSD1 INHIBITORS
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, (2015/09/22)
The present invention is directed to cyclopropylamine derivatives which are LSD1 inhibitors useful in the treatment of diseases such as cancer.
OXAZOLO [5, 4 -B] PYRIDIN- 5 -YL COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCER
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Page/Page column 21-22, (2012/06/16)
The present invention provides oxazolo[5,4-b]pyridin-5-yl compounds useful in the treatment of cancer.
COMPOUNDS USEFUL AS PROTEIN KINASES INHIBITORS
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Page/Page column 48, (2009/04/25)
The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, co
