881657-48-3

Upstream product

• 881657-58-5 tert-butyl ((3R,6S)-6-(iodomethyl)tetrahydro-2H-pyran-3-yl)carbamate 
• 86-93-1 1-Phenyl-1H-tetrazole-5-thiol 
• 603130-11-6 (2S,5R)-5-[(tert-butoxycarbonyl)amino]-2-[(tert-butyldimethylsilanyloxy)methyl]-2,5-dihydro-6H-pyran 
• 881656-86-6 tert-butyl ((3R,6S)-6-(hydroxymethyl)-3,6-dihydro-2H-pyran-3-yl)carbamate 
• 950512-61-5 toluene-4-sulfonic acid (2S,5R)-5-tert-butoxycarbonylamino-tetrahydro-pyran-2-ylmethyl ester 
• 603130-12-7 1,5-anhydro-2-[(tert-butoxycarbonyl)amino]-2,3,4-trideoxy-D-erythro-hexitol 
• 708980-46-5 1-phenyl-1H-tetrazole-5-thiol 

Downstream Products

• 881657-49-4 tert-butyl ((3R,6S)-6-(((1-phenyl-1H-tetrazol-5-yl)sulfonyl)-methyl)tetrahydro-2H-pyran-3-yl)carbamate 

Relevant academic research and scientific papers

Design, synthesis, and characterization of novel tetrahydropyran-based bacterial topoisomerase inhibitors with potent anti-gram-positive activity

There is an urgent need for new antibacterial drugs that are effective against infections caused by multidrug-resistant pathogens. Novel nonfluoroquinolone inhibitors of bacterial type II topoisomerases (DNA gyrase and topoisomerase IV) have the potential

3-AMINO-6-(1-AMINO-ETHYL)-TETRAHYDROPYRAN DERIVATIVES

The invention relates to antibacterial compounds of formula I wherein R1 represents halogen or alkoxy; U and W each represent N, V represents CH and R2 represents H or F, or U and V each represent CH, W represents N and R2

ANTIBIOTIC COMPOUNDS

The invention relates to selected antibiotics of formula (Al) wherein R1 represents alkyl, alkoxy, haloalkoxy, halogen or cyano; one or two of U, V, W and X represent(s) N, the remaining represent CH, or, in case of U, V and/or W, may also repr