881667-67-0

Basic information

• Product Name: 6-[(2S,4S)-6-Benzyloxy-2-hydroxy-4-(4-methoxy-benzyloxy)-hexyl]-2,2-dimethyl-[1,3]dioxin-4-one
• Synonyms: 6-[(2S,4S)-6-Benzyloxy-2-hydroxy-4-(4-methoxy-benzyloxy)-hexyl]-2,2-dimethyl-[1,3]dioxin-4-one
• CAS NO: 881667-67-0
• Molecular Weight: 470.563
• Mol File: 881667-67-0.mol

Chemical Properties

• CAS DataBase Reference: 6-[(2S,4S)-6-Benzyloxy-2-hydroxy-4-(4-methoxy-benzyloxy)-hexyl]-2,2-dimethyl-[1,3]dioxin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[(2S,4S)-6-Benzyloxy-2-hydroxy-4-(4-methoxy-benzyloxy)-hexyl]-2,2-dimethyl-[1,3]dioxin-4-one(881667-67-0)
• EPA Substance Registry System: 6-[(2S,4S)-6-Benzyloxy-2-hydroxy-4-(4-methoxy-benzyloxy)-hexyl]-2,2-dimethyl-[1,3]dioxin-4-one(881667-67-0)

Safety Data

• Hazardous Substances Data: 881667-67-0(Hazardous Substances Data)

Upstream product

• 130573-43-2 (2,2-dimethyl-6-methylene-6H-1,3-dioxin-4-yloxy)trimethylsilane 
• 215160-79-5 (3S)-5-benzyloxy-3-(4-methoxybenzyloxy)pentanal 
• 5394-63-8 2,2,6-trimethyl-4H-1,3-dioxin-4-one 

Downstream Products

• 215160-87-5 (2R,4S,6R,8S,10S)-8-(2-Benzyloxy-ethyl)-4-methyl-2-vinyl-1,7-dioxa-spiro[5.5]undecane-4,10-diol 
• 881667-62-5 6-[(2S,4S)-6-Benzyloxy-2-benzyloxymethoxy-4-(4-methoxy-benzyloxy)-hexyl]-2-butoxy-2,3-dihydro-pyran-4-one 
• 881667-63-6 2-[(2S,4S)-6-Benzyloxy-2-benzyloxymethoxy-4-(4-methoxy-benzyloxy)-hexyl]-pyran-4-one 
• 881667-68-1 (2R,4S,6R,8S,10S)-8-(2-Benzyloxy-ethyl)-10-benzyloxymethoxy-4-methyl-2-vinyl-1,7-dioxa-spiro[5.5]undecan-4-ol 
• 881667-64-7 2-((2S,4S)-6-Benzyloxy-2-benzyloxymethoxy-4-hydroxy-hexyl)-pyran-4-one 
• 881667-65-8 (6R,8S,10S)-8-(2-Benzyloxy-ethyl)-10-benzyloxymethoxy-1,7-dioxa-spiro[5.5]undec-2-en-4-one 
• 881667-61-4 6-[(2S,4S)-6-Benzyloxy-2-benzyloxymethoxy-4-(4-methoxy-benzyloxy)-hexyl]-2,2-dimethyl-[1,3]dioxin-4-one 

Relevant articles and documents

A hetero-Diels-Alder approach to complex pyrones: An improved synthesis of the spongistatin AB spiroketal

The conversion of a substituted dioxinone to a pyrone was used in an improved synthesis of the AB spiroketal subunit of the spongistatins. This transformation occurred via a hetero-Diels-Alder reaction of an acyl ketene with butyl vinyl ether. A double diastereoselective Mukaiyama aldol reaction is used to provide the hetero-Diels-Alder precursor.