881677-08-3

Usage

Molecular structure

1H-Pyrrole-3-carboxaldehyde, 1-[(4-cyanophenyl)sulfonyl]-5-(2-fluorophenyl)contains a pyrrole ring with a carboxaldehyde group and a sulfonyl group attached to it.

Attached groups

The compound has a 2-fluorophenyl group and a 4-cyanophenyl group attached to the pyrrole ring.

Potential applications

The compound may have potential applications in the field of organic synthesis, pharmaceuticals, and materials science.

Unique structure

The unique structure and potential reactivity of 1H-Pyrrole-3-carboxaldehyde, 1-[(4-cyanophenyl)sulfonyl]-5-(2-fluorophenyl)make it a valuable compound for further research.

Medicinal chemistry and drug development

The presence of the fluorophenyl and cyanophenyl groups, which are known for their biological activities and potential therapeutic applications, make 1H-Pyrrole-3-carboxaldehyde, 1-[(4-cyanophenyl)sulfonyl]-5-(2-fluorophenyl)- of interest for further research in medicinal chemistry and drug development.

Upstream product

• 445-27-2 2'-Fluoroacetophenone 
• 881673-98-9 ethyl 2-cyano-4-(2-fluorophenyl)-4-oxobutanoate 
• 881674-01-7 ethyl 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate 
• 881674-06-2 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylic acid ethyl ester 
• 655-15-2 2-bromo-2'-fluoroacetophenone 
• 881674-56-2 5-(2-fluorophenyl)-1H-pyrrole-3-carboxaldehyde 
• 49584-26-1 p-cyanobenzenesulfonyl chloride 

Relevant academic research and scientific papers

Proton pump inhibitors

A proton pump inhibitor containing a compound represented by the formula (I) wherein X and Y are the same or different and each is a bond or a spacer having 1 to 20 carbon atoms in the main chain, R 1 is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, R 2 , R 3 and R 4 are the same or different and each is a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted thienyl group, an optionally substituted benzo[b]thienyl group, an optionally substituted furyl group, an optionally substituted pyridyl group, an optionally substituted pyrazolyl group, an optionally substituted pyrimidinyl group, an acyl group, a halogen atom, a cyano group or a nitro group, R 5 and R 6 are the same or different and each is a hydrogen atom or an optionally substituted hydrocarbon group, which has a superior proton pump action and shows an antiulcer activity and the like after conversion to a proton pump inhibitor in the body, or a salt thereof. or a prodrug thereof is provided.

PROTON PUMP INHIBITORS

A proton pump inhibitor containing a compound represented by the formula (I) wherein X and Y are the same or different and each is a bond or a spacer having 1 to 20 carbon atoms in the main chain, R1 is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, R2, R3 and R4 are the same or different and each is a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted thienyl group, an optionally substituted benzo[b]thienyl group, an optionally substituted furyl group, an optionally substituted pyridyl group, an optionally substituted pyrazolyl group, an optionally substituted pyrimidinyl group, an acyl group, a halogen atom, a cyano group or a nitro group, R5 and R6 are the same or different and each is a hydrogen atom or an optionally substituted hydrocarbon group, which has a superior proton pump action and shows an antiulcer activity and the like after conversion to a proton pump inhibitor in the body, or a salt thereof. or a prodrug thereof is provided.

PROTON PUMP INHIBITORS

Proton pump inhibitors which have excellent proton pumping activity and which can be converted in vivo into proton pump inhibitors to exhibit antiulcer effect and so on, containing compounds represented by the general formula (I) or salts thereof or prodrugs of the same: (I) wherein X and Y are each independently a free valency or a spacer whose main chain has 1 to 20 carbon atoms; R1 is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group; R2, R3 and R4 are each independently hydrogen, an optionally substituted hydrocarbon group, optionally substituted thienyl, optionally substituted benzo[b]thienyl, optionally substituted furyl, optionally substituted pyridyl, optionally substituted pyrazolyl, optionally substituted pyrimidinyl, acyl, halogeno, cyano, or nitro; and R5 and R6 are each independently hydrogen or an optionally substituted hydrocarbon group.