881733-36-4

Basic information

• Product Name: Vonoprazan Impurity 2
• Synonyms: Vonoprazan Impurity 2;Vonoprazan Impurity 4 Fumarate;1-(5-(4-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine
• CAS NO: 881733-36-4
• Molecular Formula: C17H16FN3O2S
• Molecular Weight: 345.39
• Mol File: 881733-36-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 534.7±60.0 °C(Predicted)
• Appearance: /
• Density: 1.31±0.1 g/cm3(Predicted)
• PKA: 9.11±0.10(Predicted)
• CAS DataBase Reference: Vonoprazan Impurity 2(CAS DataBase Reference)
• NIST Chemistry Reference: Vonoprazan Impurity 2(881733-36-4)
• EPA Substance Registry System: Vonoprazan Impurity 2(881733-36-4)

Safety Data

• Hazardous Substances Data: 881733-36-4(Hazardous Substances Data)

Usage

General Description

Vonoprazan Impurity 2 is a chemical compound that is classified as an impurity of vonoprazan, a medication used to treat acid-related conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers. The chemical structure of Vonoprazan Impurity 2 is closely related to vonoprazan, but it contains impurities that may affect its purity and potency. It is important to regulate and monitor the levels of Vonoprazan Impurity 2 in vonoprazan medications to ensure the safety and effectiveness of the drug for patients.

Upstream product

• 881678-31-5 tert-butyl {[5-(4-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]methyl}methylcarbamate 

Relevant articles and documents

Proton pump inhibitors

A proton pump inhibitor containing a compound represented by the formula (I) wherein X and Y are the same or different and each is a bond or a spacer having 1 to 20 carbon atoms in the main chain, R 1 is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, R 2 , R 3 and R 4 are the same or different and each is a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted thienyl group, an optionally substituted benzo[b]thienyl group, an optionally substituted furyl group, an optionally substituted pyridyl group, an optionally substituted pyrazolyl group, an optionally substituted pyrimidinyl group, an acyl group, a halogen atom, a cyano group or a nitro group, R 5 and R 6 are the same or different and each is a hydrogen atom or an optionally substituted hydrocarbon group, which has a superior proton pump action and shows an antiulcer activity and the like after conversion to a proton pump inhibitor in the body, or a salt thereof. or a prodrug thereof is provided.