881829-67-0Relevant academic research and scientific papers
Design and modular parallel synthesis of a MCR derived α-helix mimetic protein-protein interaction inhibitor scaffold
Antuch, Walfrido,Menon, Sanjay,Chen, Quin-Zene,Lu, Yingchun,Sakamuri, Sukumar,Beck, Barbara,Schauer-Vukasinovic, Vesna,Agarwal, Seema,Hess, Sibylle,Doemling, Alexander
, p. 1740 - 1743 (2006)
A terphenyl α-helix mimetic scaffold recognized to be capable of disrupting protein-protein interactions was structurally morphed into an easily amenable and versatile multicomponent reaction (MCR) backbone. The design, modular in-parallel library synthes
