881850-14-2

Basic information

• Product Name: 2-Butenal, 3-(4-bromophenyl)-
• CAS NO: 881850-14-2
• Molecular Formula: C10H9BrO
• Molecular Weight: 225.085
• Mol File: 881850-14-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Butenal, 3-(4-bromophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butenal, 3-(4-bromophenyl)-(881850-14-2)
• EPA Substance Registry System: 2-Butenal, 3-(4-bromophenyl)-(881850-14-2)

Safety Data

• Hazardous Substances Data: 881850-14-2(Hazardous Substances Data)

Upstream product

• 99-90-1 para-bromoacetophenone 
• 76346-17-3 3-(4-bromophenyl)but-2-enoic acid ethyl ester 
• 26939-18-4 2,4,4,6-tetramethyl-5,6-dihydro-4H-1,3-oxazine 

Downstream Products

• 1332645-29-0 (R)-4-(4-bromophenyl)-6-(trifluoromethyl)-6-phenyl-5,6-dihydro-2H-pyran-2-one 
• 1332645-55-2 (R)-1-methyl-4'-(4-bromophenyl)spiro[indoline-3,2'-pyran]-2,6'(1H,3'H)-dione 

Relevant articles and documents

Carbene-Catalyzed Formal [3+3] Cycloaddition Reaction for Access to Substituted 2-Phenylbenzothiazoles

A carbene-catalyzed oxidative cycloaddition reaction is developed for efficient access to multi-functionalized 2-phenylbenzothiazoles. A broad scope of heavily substituted arenes bearing 2-benzothiazole groups have been prepared in good to excellent yields. The remote C(sp2)–H bond in the substituted arene products can be activated by Pd catalysts in regio-selective fashion with the direction of the 2-benzothiazole groups.

Carbene-catalyzed enal γ-carbon addition to α-ketophosphonates for enantioselective access to bioactive 2-pyranylphosphonates

A carbene-catalyzed enantioselective [4+2] cycloaddition reaction between α,β-unsaturated aldehydes and α-ketophosphonates is developed. The reaction affords chiral 2-pyranylphosphonates with excellent enantioselectivities. The optically enriched phosphonate products bear multiple functional groups, including unsaturated lactone and phosphonate moieties that often lead to unique bio-activities. Preliminary studies show that the products from our reactions exhibit anti-bacterial (X. oryzae pv. oryzae) and anti-viral (Tobacco Mosaic Virus) activities for potential use in plant protection.

Oxidative γ-addition of enals to trifluoromethyl ketones: Enantioselectivity control via lewis acid/n-heterocyclic carbene cooperative catalysis

An oxidative γ-functionalization of enals under N-heterocyclic carbene (NHC) catalysis to give unsaturated δ-lactones is disclosed. Enantioselectivity control involving the relatively remote enal γ-carbon was achieved via Lewis acid [Sc(OTf)3 or combined Sc(OTf) 3/Mg(OTf)2] and NHC cooperative catalysis.