881852-18-2Relevant academic research and scientific papers
Using cross-metathesis to couple L-phenylalanine to a macrocyclic lactam
Enholm, Eric,Low, Tammy
, p. 2272 - 2276 (2006)
Grubbs' second generation ruthenium catalyst was used to couple the amino acid L-phenylalanine to a 17-membered lactam, using cross-metathesis with an E-alkene favored in the process. The best coupling conditions gave the product in 48% yield. The reversi
