88186-32-7Relevant academic research and scientific papers
A 2 - aryl - 2 - oxazoline preparation method
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Paragraph 0010-0020, (2017/06/21)
The invention discloses a 2-aryl-2-oxazoline preparation method and belongs to the field of chemistry. According to the method, an aryl-amide compound and 1,2-dichloroethane are reacted for synthesis, and the synthesis reaction is conducted under the alka
Oxazoline-Promoted Rh-Catalyzed C-H Amidation of Benzene Derivatives with Sulfonamides and Trifluoroacetamide. A Comparative Study
Maiden, Tracy M.M.,Swanson, Stephen,Procopiou, Panayiotis A.,Harrity, Joseph P.A.
, p. 10641 - 10650 (2016/11/29)
A Rh-catalyzed ortho-amidation of 2-aryloxazolines offers an efficient and direct route to a range of sulfonamides. The scope of the reaction is very broad with respect to sulfonamide substrate, but the position and electronic nature of the substituents on the aryl moiety of the oxazoline lead to a surprising modulation of reactivity. The reactivity of sulfonamides in comparison to trifluoroacetamide is compared, the latter undergoing Rh-catalyzed amidation more rapidly.
Functionalizations of Mixtures of Regioisomeric Aryllithium Compounds by Selective Trapping with Dichlorozirconocene
Castell-Mic, Alicia,Herbert, Simon A.,Len, Thierry,Bein, Thomas,Knochel, Paul
supporting information, p. 401 - 404 (2016/01/25)
The reaction of mixtures of aryllithium regioisomers obtained either by directed lithiation or by Br/Li exchange with substoichiometric amounts of Cp2ZrCl2 proceeds with high regioselectivity. The least sterically hindered regioisome
The Use of 2-Oxazolidinone as a Latent Aziridine Equivalent. I. A Facile Method for the Preparation of 2-Substituted Oxazolines
Poindexter, Graham S.
, p. 1431 - 1433 (2007/10/02)
Ring-opening reaction of 2-oxazolidinone with acid chlorides followed by treatment with aqueous sodium hydroxide yields 2-substituted oxazolines.
