881897-25-2Relevant academic research and scientific papers
A short total synthesis of (±)-aspidospermidine
Sharp, Lisa A.,Zard, Samir Z.
, p. 831 - 834 (2006)
A cascade radical cyclization starting from an amidyl radical has been used for the construction of (±)-aspidospermidine. This approach has also been developed for the preparation of a tricycle whose framework is contained in the stemona alkaloids.
Amidyls in radical cascades. The total synthesis of (±)-aspidospermidine and (±)-13-deoxyserratine
Callier-Dublanchet, Anne-Claude,Cassayre, Jér?me,Gagosz, Fabien,Quiclet-Sire, Béatrice,Sharp, Lisa A.,Zard, Samir Z.
, p. 4803 - 4816 (2008/09/21)
Concise routes to aspidospermidine and 13-deoxyserratine are described, hinging on a cascade starting from an amidyl radical and allowing the construction of the key indolizidine cores in one step.
