881997-92-8

Basic information

• Product Name: 4,5-dibromo-1-methyl-2-phenyl-1H-imidazole
• Synonyms: 4,5-dibromo-1-methyl-2-phenyl-1H-imidazole
• CAS NO: 881997-92-8
• Molecular Weight: 315.995
• Mol File: 881997-92-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4,5-dibromo-1-methyl-2-phenyl-1H-imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-dibromo-1-methyl-2-phenyl-1H-imidazole(881997-92-8)
• EPA Substance Registry System: 4,5-dibromo-1-methyl-2-phenyl-1H-imidazole(881997-92-8)

Safety Data

• Hazardous Substances Data: 881997-92-8(Hazardous Substances Data)

Upstream product

• 56338-00-2 4,5-dibromo-2-phenyl-1H-imidazole 
• 74-88-4 methyl iodide 
• 1003-50-5 4,5-dibromo-1-methyl-1H-imidazole 
• 591-50-4 iodobenzene 
• 670-96-2 2-Phenylimidazole 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 1424382-11-5 C₁₈H₁₅Br₂N₂O⁽¹⁺⁾*Br^(1-) 

Relevant articles and documents

Facile synthetic method for diverse polyfunctionalized imidazoles by means of pd-catalyzed C-H bond arylation of N -methyl-4,5-dibromoimidazole

C-H bond-selective arylation reaction of 4,5-dibromoimidazole with aryl iodides, catalyzed by the palladium-1,10-phenanthroline complex [Pd(phen) 2](PF6)2, has been developed. The process tolerates the presence of a variety of functional groups on the aryl halide substrates. The products formed in these reactions were transformed to a variety of polyfunctionalized imidazoles by taking advantage of selective reactions of remaining C-Br bonds.

Aminobenzoannulated hetero- and carbocycles from 2-azahepta-2,4-dien-6- ynyllithium compounds: Scope and limitation of a novel benzoannulation reaction

Deprotonation of the N-benzylhetarylmethanimines 9, 12, 15, and 18 at -78°C with subsequent warming to room temperature over 16 hours and treatment with electrophiles furnished polysubstituted aminobenzoannulated heterocycles 19-25 in good to excellent yields. In a similar fashion, the deprotonation of the N-allyl-2-(alk-1-ynyl)phenylmethanimines 26 and 27 led to 2-vinylnaphthalen-1-amines 28 and 29, respectively, in moderate yields. The reaction of N-[(trimethylsilyl)methyl]imine 31 afforded naphthalen-1-amine 33, unsubstituted at the ortho position after removal of the trimethylsilyl group. The deprotonation of imine 34, bearing a trimethylsilyl group on the C≡C bond, gave none of expected amines, but the substituted imine 35, whose structure was identified using 2D NMR spectroscopy. Georg Thieme Verlag Stuttgart.