88208-65-5

Upstream product

• 88208-61-1 3-[(Z)-2,2-Diphenyl-benzo[1,3]dioxol-4-ylimino]-2,2-dimethyl-N-phenyl-propionamide 
• 72553-33-4 methyl 2,2-diphenylbenzo[d][1,3]dioxole-4-carboxylate 
• 88208-58-6 2,3-diphenylmethylenedioxyaniline 
• 54888-41-4 2,3-<(diphenylmethylene)dioxy>benzoic acid 
• 88215-60-5 C₄₄H₃₅N₂O₄P 
• 701-99-5 Phenoxyacetyl chloride 

Downstream Products

• 88208-66-6 (+/-)-7,8-dihydroxy-3,3-dimethyl-2-phenoxyacetamido-2a,3-dihydroazeto<1,2-a>quinoline-1,4(2H)-dione 

Relevant academic research and scientific papers

New Polycyclic β-Lactams. Synthesis of 2a,3-Dihydroazetoquinoline-1,4(2H)-diones, Structural Analogues of the Carbacephalosporin Antibiotics

A method has been developed for the preparation of dihydroxydihydroazetoquinoline-1,4(2H)-diones (1).The synthesis involved, as a key step, the completion of the polycyclic β-lactam system by a modified Bischler-Napieralski reaction.It was illustrated by the synthesis of (+/-)-7,8-dihydroxy-3,3-dimethyl-2-phenoxyacetamido-2a,3-dihydroazetoquinoline-1,4(2H)-dione (20), which is structurally related to the carbacephalosporin antibiotics.