88208-67-7Relevant academic research and scientific papers
New Polycyclic β-Lactams. Synthesis of 2a,3-Dihydroazetoquinoline-1,4(2H)-diones, Structural Analogues of the Carbacephalosporin Antibiotics
Bachi, Mario D.,Klein, Joseph
, p. 1925 - 1928 (1983)
A method has been developed for the preparation of dihydroxydihydroazetoquinoline-1,4(2H)-diones (1).The synthesis involved, as a key step, the completion of the polycyclic β-lactam system by a modified Bischler-Napieralski reaction.It was illustrated by the synthesis of (+/-)-7,8-dihydroxy-3,3-dimethyl-2-phenoxyacetamido-2a,3-dihydroazetoquinoline-1,4(2H)-dione (20), which is structurally related to the carbacephalosporin antibiotics.
