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Stereoselective Synthesis of Crinosterol
Anastasia, Mario,Allevi, Pietro,Ciuffreda, Pierangela,Fiecchi, Alberto
, p. 2365 - 2367 (2007/10/02)
A stereoselective synthesis of crinosterol, (22E,24S)-ergosta-5,22-dien-3β-ol, was developed from (20S)-6β-acetoxy-3α,5-cyclo-5α-pregnane-20-carbaldehyde using the Claisen rearrangement of an appropriate precursor of established absolute configuration.
