882562-39-2

Usage

Uses

Used in Organic Synthesis:
1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-ylboronic acid is used as a building block in organic synthesis for its ability to form stable complexes with certain biomolecules. This property makes it valuable in the development of pharmaceuticals and agrochemicals.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-ylboronic acid is utilized as a key component in the synthesis of potential drug candidates, contributing to the advancement of drug discovery.
Used in Materials Science:
1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-ylboronic acid is employed in materials science for its potential applications in creating new materials with unique properties.
Used in Chemical Biology:
In chemical biology, 1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-ylboronic acid serves as a valuable tool for studying biological processes due to its ability to interact with biomolecules, aiding in the understanding of complex biological systems.
Overall, 1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-ylboronic acid is a multifaceted compound with a broad spectrum of applications across different industries, showcasing its significance in modern scientific research and development.

InChI:InChI=1/C14H13BN2O4S/c1-10-4-6-11(7-5-10)22(20,21)17-9-13(15(18)19)12-3-2-8-16-14(12)17/h2-9,18-19H,1H3

Upstream product

• 664982-01-8 3-iodo-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridine 
• 226085-18-3 3-bromo-1-(4-methylbenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine 
• 7732-18-5 water 
• 73183-34-3 bis(pinacol)diborane 
• 74420-15-8 3-bromo-1H-pyrrolo[2,3-b]pyridine 
• 271-63-6 7-Azaindole 
• 5419-55-6 Triisopropyl borate 

Downstream Products

• 1417421-80-7 (R)-2-methyl-2-(2-(1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-ylamino)butanoic acid 
• 944842-54-0 decernotinib 
• 1417421-95-4 methyl 2-methyl-2-((2-(1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)butanoate 
• 1417421-89-6 C₂₁⁽¹³⁾C₄H₂₅F₃N₄⁽¹⁵⁾N₂O₃S 
• 866545-91-7 1-(4-methylbenzenesulfonyl)-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine 
• 1227866-35-4 4-[(3,5-difluorobenzyl)amino]-6-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridine-3-carboxyamide 
• 1227866-34-3 4-[(3,5-difluorobenzyl)amino]-6-{1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-3-yl}pyridine-3-carboxyamide 

Relevant academic research and scientific papers

DERIVATIVES OF QUINOLINE AS INHIBITORS OF DYRK1A AND/OR DYRK1B KINASES

The present invention relates to the compound of formula (I) and salts, stereoisomers, tautomers or N-oxides thereof. The present invention is further concerned with the use of such a compound or salt, stereoisomer, tautomer or N-oxide thereof as medicament and a pharmaceutical composition comprising said compound.

PHARMACEUTICAL COMBINATIONS USEFUL FOR TREATING RHEUMATOID ARTHRITIS

The present invention provides a method of treating or lessening the severity of a disease or disorder mediated by an abnormal immune response (e.g., rheumatoid arthritis) comprising the administration of a compound of Formula I and a corticosteroid.

METHODS FOR TREATING INFLAMMATORY DISEASES AND PHARMACEUTICAL COMBINATIONS USEFUL THEREFOR

The present invention provides a method of treating psoriasis comprising the administration of a compound of Formula I or a compound of Formula I and a co-therapy, and administrations of pharmaceutical compositions comprising a compound of Formula (I).

PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES

The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK).

METHODS FOR TREATING INFLAMMATORY DISEASES AND PHARMACEUTICAL COMBINATIONS USEFUL THEREFOR

The present invention provides method of treating or lessening the severity of a disease selected from spondyloarthropathy, systemic lupus erythematosus, rheumatoid arthritis, or any combination thereof comprising the administration of a compound of Formu