88261-52-3Relevant academic research and scientific papers
Synthesis of 5-thio-L-fucose-containing blood group antigens H-type 2 and Lewis X (Lex)
Izumi, Masayuki,Tsuruta, Osamu,Hashimoto, Hironobu,Yazawa, Shin
, p. 1809 - 1812 (1996)
Two blood group antigens, H-type 2 and Lewis X trisaccharides containing 5-thio-L-fucose instead of L-fucose, were synthesized. 2-Azido-2-deoxy-lactose derivative 11 was used as the common disaccharide intermediate. 5-Thio-L-fucosylation of the 2′-OH and 3-OH groups of 1,6-anhydro-2-azido-2-deoxy-lactose derivative by a trichloroacetimidate method gave α-linked trisaccharides stereoselectively.
t-BUTYLDIMETHYLSILYL (TBDMS) AS PROTECTIVE GROUP IN CARBOHYDRATE CHEMISTRY MIGRATION OF THE TBDMS GROUP IN TRANS-DIOL SYSTEMS
Boeckel, C. A. A. van,Aelst, S. F. van,Beetz, T.
, p. 415 - 416 (2007/10/02)
In the presence of base the t-butyldimethylsilyl (TBDMS) protective group is able to migrate between trans-diaxial hydroxyl functions of carbohydrates.
