882670-93-1

Basic information

• Product Name: 6-Bromo-2-iodoquinazoline
• Synonyms: 6-bromo-2-iodoquinazoline;Quinazoline, 6-bromo-2-iodo-
• CAS NO: 882670-93-1
• Molecular Formula: C₈H₄BrIN₂
• Molecular Weight: 334.94
• Mol File: 882670-93-1.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 427.5 °C at 760 mmHg
• Flash Point: 212.4 °C
• Appearance: /
• Density: 2.259
• Vapor Pressure: 4.05E-07mmHg at 25°C
• Refractive Index: 1.757
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6-Bromo-2-iodoquinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Bromo-2-iodoquinazoline(882670-93-1)
• EPA Substance Registry System: 6-Bromo-2-iodoquinazoline(882670-93-1)

Safety Data

• Hazardous Substances Data: 882670-93-1(Hazardous Substances Data)

Usage

General Description

6-Bromo-2-iodoquinazoline is a chemical compound with the molecular formula C8H5BrIN2. It is a quinazoline derivative that contains both bromine and iodine atoms. 6-Bromo-2-iodoquinazoline is used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is commonly utilized in the development of new drug candidates and has shown potential as a building block in medicinal chemistry research. 6-Bromo-2-iodoquinazoline is known for its versatility and ability to undergo various chemical reactions, making it a valuable tool in organic synthesis.

InChI:InChI=1/C8H4BrIN2/c9-6-1-2-7-5(3-6)4-11-8(10)12-7/h1-4H

Upstream product

• 190273-89-3 6-bromoquinazolin-2-ylamine 
• 93777-26-5 5-bromo-2-fluorobenzaldehyde 

Downstream Products

• 1408285-88-0 C₂₁H₂₃BrN₄O₃ 
• 1408285-81-3 C₃₈H₃₂F₃N₇O₃ 
• 1408285-91-5 C₃₂H₂₆F₃N₇O₂ 
• 1408285-90-4 C₃₇H₃₄F₃N₇O₄ 
• 1408285-89-1 C₂₈H₃₁N₅O₃ 
• 882663-88-9 4-methyl-3-(2-((2-(4-morpholinyl)ethyl)amino)-6-quinazolinyl)-N-(3-(trifluoromethyl)phenyl)benzamide 

Relevant articles and documents

Synthesis of novel N-aryl-4-[6-(2-fluoropyridin-3-yl)quinazolin-2-yl]-piperazine-1-carboxamide or -carbothioamide derivatives and their antimicrobial activity

A series of novel N-aryl-4-[6-(2-fluoropyridin-3-yl)quinazolin-2-yl]-piperazine-1-carboxamide or -carbothioamide derivatives was synthesized by cyclization of 5-bromo-2-fluorobenzaldehyde and guanidine carbonate in the presence of dimethylacetamide follow

TREATMENT OF FIBROSIS WITH IRE1 SMALL MOLECULE INHIBITORS

Provided herein are methods of using IRE1 small molecule inhibitors in combination therapies for treating fibrosis in a subject. The IRE1 small molecule inhibitors described herein may be used in combination therapies for treating fibrosis

Inhibitor of Bruton tyrosine kinase

The invention discloses a compound of a formula (I) with Btk inhibiting activity, wherein all variables are as defined in the description. The compound can be used for treating autoimmune diseases, heteroimmune diseases, cancers or thrombembolia. The inve