882697-82-7Relevant academic research and scientific papers
Synthesis and evaluation of a novel series of indoloisoquinolines as small molecule anti-malarial leads
Horrocks, Paul,Fallon, Samantha,Denman, Laura,Devine, Oliver,Duffy, Liam J.,Harper, Anthony,Meredith, Emma-Louise,Hasenkamp, Sandra,Sidaway, Adam,Monnery, Daniel,Phillips, Theresa R.,Allin, Steven M.
supporting information; experimental part, p. 1770 - 1773 (2012/04/04)
A group of novel synthetic indoloisoquinolines was prepared and its potential as a novel series of smallmolecule anti-malarial leads was assessed. The structure-activity relationship on variation of three distinct regions of chemical space was investigate
Complementary stereoselective conjugate addition reactions on indolo[2,3-a]quinolizine templates
Allin, Steven M.,Khera, Jagjit S.,Thomas, Christopher I.,Witherington, Jason,Doyle, Kevin,Elsegood, Mark R.J.,Edgar, Mark
, p. 1961 - 1964 (2007/10/03)
We report a new and highly stereoselective approach for the construction of a range of functionalized indolo[2,3-a]quinolizine targets from a readily available, nonracemic chiral template. The methods developed allow us to predetermine relative product st
