883106-18-1

Basic information

• Product Name: 2,6-Difluoro-3-(2-pyridnyl)-benzonitrile
• Synonyms: 2,6-Difluoro-3-(2-pyridnyl)-benzonitrile;2,6-Difluoro-3-(2-pyridinyl)benzonitrile;5'-cyano-4',6'-difluoro-2-phenylpyridine;2,6-difluoro-3-(pyridin-2-yl)benzonitrile
• CAS NO: 883106-18-1
• Molecular Formula: C₁₂H₆F₂N₂
• Molecular Weight: 216.19
• Mol File: 883106-18-1.mol

Chemical Properties

• Melting Point: 76-77℃
• Boiling Point: 314.9±42.0 °C(Predicted)
• Appearance: /
• Density: 1.32
• Storage Temp.: 2-8°C
• PKA: 3.25±0.29(Predicted)
• CAS DataBase Reference: 2,6-Difluoro-3-(2-pyridnyl)-benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Difluoro-3-(2-pyridnyl)-benzonitrile(883106-18-1)
• EPA Substance Registry System: 2,6-Difluoro-3-(2-pyridnyl)-benzonitrile(883106-18-1)

Safety Data

• Hazardous Substances Data: 883106-18-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2,6-Difluoro-3-(2-pyridnyl)-benzonitrile is utilized as a building block in the synthesis of heterocyclic compounds, which are integral to the development of pharmaceuticals and agrochemicals. Its unique structure contributes to the creation of novel molecules with potential therapeutic and pesticidal properties.
Used in Biological Imaging:
2,6-Difluoro-3-(2-pyridnyl)-benzonitrile is studied for its potential use as a fluorescent probe in biological imaging. Its fluorescent properties allow for the visualization and tracking of biological processes at the molecular level, offering valuable insights into cellular mechanisms and disease pathways.
Used in Organic Light-Emitting Diodes (OLEDs):
2,6-Difluoro-3-(2-pyridnyl)-benzonitrile is also being investigated for its application in the development of organic light-emitting diodes. Its photophysical properties make it a promising candidate for improving the efficiency and performance of OLEDs, which are widely used in display and lighting technologies.
Used in Antimicrobial Applications:
2,6-Difluoro-3-(2-pyridnyl)-benzonitrile has shown antimicrobial properties, making it a compound of interest in the development of new antimicrobial agents. Its ability to inhibit the growth of various microorganisms could contribute to the fight against antibiotic-resistant bacteria and the discovery of novel antimicrobial therapies.
Used in Anticancer Research:
Furthermore, 2,6-Difluoro-3-(2-pyridnyl)-benzonitrile has been explored for its anticancer properties. Its potential to target and inhibit the growth of cancer cells positions it as a candidate for further research and development in oncology, with the aim of identifying new therapeutic strategies for cancer treatment.

Upstream product

• 5029-67-4 2-iodopyridine 
• 871940-31-7 2,4-difluoro-3-cyanophenylboronic acid 
• 109-04-6 2-bromo-pyridine 
• 1897-52-5 2,6 difluorobenzonitrile 
• 1308400-81-8 2,6-difluoro-3-(6-methyl-4,8-dioxo-1,3,6,2-dioxazaborocan-2-yl)benzonitrile 

Downstream Products

• 1308400-82-9 6-fluoro-2-hydroxy-3-(pyridin-2-yl)benzonitrile 
• 1308400-88-5 2-fluoro-6-hydroxy-3-(pyridin-2-yl)benzonitrile 
• 1308400-83-0 2,6-difluoro-3-(pyridin-2-yl)benzamide 
• 1308400-84-1 6-fluoro-2-(octyloxy)-3-(pyridin-2-yl)benzonitrile 
• 1308400-89-6 2-fluoro-6-(octyloxy)-3-(pyridin-2-yl)benzonitrile 

Relevant articles and documents

Design of pyridinylphosphinate-based blue iridium phosphors for high-efficiency organic light-emitting diodes

At present, cyclometalated iridium (Ir)(iii) complexes are the most promising emitters for OLEDs. Contrary to well-developed Ir(iii)-based red and green phosphorescent complexes, the efficient blue emitters are limited and the performances of blue OLEDs are still not satisfactory. Inspired by this, we designed two novel blue Ir(iii) complexes employing 2-(2,4-difluoropyridyl)pyridine (dfpypy) and 2,6-difluoro-3-(pyridin-2-yl)benzonitrile (FCN) as the main ligands, respectively, and phenyl(pyridin-2-yl)phosphinate (ppp) as the ancillary ligand. The rational design of the molecular structure makes the two complexes achieve blue emission and possess good electron mobility simultaneously. The devices based on the Ir(iii) phosphors exhibited good electroluminescence performances with low turn-on voltages, a peak current efficiency of 24.51 cd A?1, a maximum external quantum efficiency of 12.4%, a peak power efficiency of 21.99 lm W?1and low efficiency roll-off. These results provide an effective strategy for the future molecular design of blue Ir(iii) complexes with good electron transport property for OLEDs.

Organoiridium complex for organic electroluminescent elements

The present invention provides an organometallic complex having a high quantum efficiency even in a polymer thin film as a emitting material for organic electroluminescent (EL) element. The present invention relates to an organoiridium complex for an organic electroluminescent element represented by the following Formula; wherein a C—N ligand including two atomic groups (A1, A2), and a β-diketone ligand in line symmetry having two tert-butyl-substituted phenyl groups are coordinated with an iridium atom. The organoiridium complex of the present invention has a high quantum efficiency even in a polymer thin film with respect to green to yellow electroluminescence. (In the aforementioned Formula, R1, R2, and R3 are each a tert-butyl group or a hydrogen atom, and have at least one tert-butyl group; they may bond each other to thereby form a saturated hydrocarbon ring, when having two tert-butyl groups; A1, A2 are each an unsaturated hydrocarbon ring, at least one is a single ring, and at least one is a heterocyclic ring).

Iridium complex, preparation method of iridium complex and organic electroluminescence device using iridium complex

The invention relates to one type of iridium complex, a preparation method of the iridium complex and an organic electroluminescence device using the iridium complex. The series of iridium complex molecule comprises two benzene dipyridine derivatives serving as main ligands and auxiliary ligands containing nitrogen heterocycle phosphoric acid structures. Compared with the iridium complex which has been widely researched and reported, the type of novel iridium complex covered by the invention has the advantages of high light emitting efficiency, stable chemical property and high possibility of sublimation and purification; meanwhile, due to the introduction of strong electron phosphoric acid ligand structures, the light emitting color of the complex can be effectively regulated; by modifying the molecule structures of the main ligands and the auxiliary ligands, the light emitting position of the complex in the blue light wavelength range can be adjusted, so that the convenience is brought to design and production of organic electroluminescence displays and lighting sources; meanwhile, the series of novel iridium complex introduced by the invention is simple in synthesis method, high in yield and flexible in chemical modification on the main ligands and the auxiliary ligands.

Nucleophilic substitution of fluorine atoms in 2,6-difluoro-3-(pyridin-2- yl)benzonitrile leading to soluble blue-emitting cyclometalated Ir(III) complexes

New functionalized phenylpyridine ligands and their derived heteroleptic cyclometalated Ir(III) complexes have been synthesized. The complexes possess a combination of important properties: (i) blue emission, (ii) good photoluminescence quantum yields, an